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Tumor volume, luxury perfusion, and regional blood volume changes in man visualized by subtraction computerized tomography

1976; American Association of Neurological Surgeons; Volume: 44; Issue: 4 Linguagem: Inglês

10.3171/jns.1976.44.4.0449

1933-0693

Richard D. Penn, Randal L. Walser, D. Kurtz, L V Ackerman,

Advanced X-ray and CT Imaging

✓ Computer and photographic methods for producing subtractions of computerized axial tomographic (CAT) scans have been developed. By subtracting point for point a normal scan from one taken after intravenous infusion of contrast material, a picture of the contrast in the cerebral vessels is created. By this method, tumor size and degree of vascularity may be assessed. Furthermore, abnormalities in perfusion and changes in blood volume due to mass effects and edema may be detected. Subtracting scans should add to the diagnostic potential of CAT and provide a noninvasive way to study vascular changes in cerebral disease.