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Theoretical approaches to drug design and biological activity: II. Multivariate structure‐activity relationships in combination with the multivariate bioassay (MASCA Model)

1983; Wiley; Volume: 3; Issue: 4 Linguagem: Inglês

10.1002/med.2610030404

1098-1128

Peter P. Mager,

Gene Regulatory Network Analysis

Medicinal Research ReviewsVolume 3, Issue 4 p. 435-498 Article Theoretical approaches to drug design and biological activity: II. Multivariate structure-activity relationships in combination with the multivariate bioassay (MASCA Model)† Peter P. Mager, Peter P. Mager Research Group for Pharmacochemistry, Karl Marx University, DDR-7010 Leipzig, Liebigstrasse 27, German Democratic Republic Peter P. Mager was born in 1946 in Klostergeringswalde/Saxonia. He studied medicine and, in part chemistry, at the Universities of Leipzig and Halle, and obtained the medical full approbation in 1973 and the M.D. degree in 1974 (neurophysiology and neuropharmacology). He spent the following years in seoeral theoretical institutes and the Department of Internal Medicine of the Psychiatric Hosptial of Leipzig; pharmacologist and toxicologist education and degree in 1978; D.Sc. in 1981 (biomathematics in drug design). He is Head of the Research Group for Pharmacochemistry of the University of Leipzig. Dr. Mager is the author of over 140 articles published in oarious professional periodicals and books, and holds membership in seoeral scientific societies. His main research activity lies in the areas of multivariate statistics and design applied to pharmacochernistry, QSAR, applied system fheory and rhythms, and toxicology.Search for more papers by this author Peter P. Mager, Peter P. Mager Research Group for Pharmacochemistry, Karl Marx University, DDR-7010 Leipzig, Liebigstrasse 27, German Democratic Republic Peter P. Mager was born in 1946 in Klostergeringswalde/Saxonia. He studied medicine and, in part chemistry, at the Universities of Leipzig and Halle, and obtained the medical full approbation in 1973 and the M.D. degree in 1974 (neurophysiology and neuropharmacology). He spent the following years in seoeral theoretical institutes and the Department of Internal Medicine of the Psychiatric Hosptial of Leipzig; pharmacologist and toxicologist education and degree in 1978; D.Sc. in 1981 (biomathematics in drug design). He is Head of the Research Group for Pharmacochemistry of the University of Leipzig. Dr. Mager is the author of over 140 articles published in oarious professional periodicals and books, and holds membership in seoeral scientific societies. His main research activity lies in the areas of multivariate statistics and design applied to pharmacochernistry, QSAR, applied system fheory and rhythms, and toxicology.Search for more papers by this author First published: October/December 1983 https://doi.org/10.1002/med.2610030404Citations: 9 † Theoretical Approaches to Drug Design and Biological Activity: “Critical Comments to the Use of Mathematical Methods Applied to Univariate and Multivariate Quantitative Structure-Activity Relationships” (QSAR) (see Med. Res. Rev., 2, 93, January–March (1982). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. 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Citing Literature Volume3, Issue4October/December 1983Pages 435-498 ReferencesRelatedInformation