Uterine papillary serous carcinoma--the KK Hospital experience.
1998; National Institutes of Health; Volume: 27; Issue: 5 Linguagem: Inglês
Autores Tópico(s)
Cervical Cancer and HPV Research
ResumoA review of 355 cases of endometrial cancer treated at the KK Gynaecological Cancer Centre from June 1987 to June 1997 revealed 19 cases (5.3%) of uterine papillary serous carcinoma (UPSC), a clinically aggressive and pathologically distinct variant of adenocarcinoma which closely resembles ovarian papillary serous carcinoma. The majority of UPSC presented as late stage disease with 79% showing extrauterine disease. Twelve of 15 patients also had lymphovascular space invasion. Of the 19 cases, 15 had total hysterectomy and bilateral salpingo-oophorectomy with or without omentectomy and lymphadenectomy. Two had omental biopsy only and another 2 had dilatation and curettage only. The overall median survival in the series was 15 months. Twelve patients had died of disease (67%). Early stage disease seemed to confer a better prognosis. The poor prognosis is frequently ascribed to its tendency to present at a late stage.
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