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RECOGNITION AND RADIUM TREATMENT OF INFECTED AND HYPERTROPHIED LYMPHOID TISSUE IN THE NASOPHARYNX: Preliminary Report

1943; American Medical Association; Volume: 37; Issue: 3 Linguagem: Inglês

10.1001/archotol.1943.00670030444012

1538-361X

GILBERT E. FISHER,

Effects of Radiation Exposure

It has been known for years that lymphoid tissue is readily affected by exposure to roentgen rays and radium. Heinlke 1 in 1905, in a study of the biologic effects of roentgen rays on lymphoid tissue, noted that after long exposure of animals to radiation both the circulating lymphocytes and the lymphoid tissue were almost completely destroyed. This observation led to the use of the roentgen ray in the treatment of lymphatic leukemia and in reducing the size of the enlarged spleen and lymph nodes occurring in other diseases. Akaiwa and Takeshima, 2 in 1930, carried out experiments on the effects of irradiation of the lymph nodes in the popliteal spaces of rabbits. Thirty minutes after exposure to radiation the lymph follicles of these nodes were enlarged. After one hour the nuclei of many of the cells began to show disintegration, which reached its height in from two to six hours. From