Portal de Periódicos da CAPES

Hematologic Parameters and Angiographic Progression of Coronary Atherosclerosis

2011; SAGE Publishing; Volume: 63; Issue: 3 Linguagem: Inglês

10.1177/0003319711412763

1940-1574

Nihat Kalay, Orhan Doğdu, Fatih Koç, Mikail Yarlıoğlueş, İdris Ardıç, Mahmut Akpek, Davran Çiçek, Abdurrahman Oğuzhan, Ali Ergin, Mehmet Güngör Kaya,

Venous Thromboembolism Diagnosis and Management

Hematologic parameters have prognostic importance in cardiovascular disease. However, the relation between atherosclerosis progression and hematologic parameters is not well defined. A total of 394 patients requiring repeat coronary angiography were included in the study. According to angiography, patients were divided into 2 groups, progressive (n = 196) and nonprogressive (n = 198) diseases. Hematologic parameters including mean platelet volume (MPV) and neutrophil/lymphocyte (N/L) ratio were measured. Glucose, creatinine, and cholesterol were significantly higher in the progressive group. Mean platelet volume count was similar in both groups. The N/L ratio was significantly higher in the progressive group (5.0 ± 5.1 vs 3.2 ± 3; P = .001). In multivariate analysis, the N/L ratio was significantly related with progression (relative risk [RR]: 2.267, 95% CI: 1.068-4.815, P = .03). Progression rate was significantly high in patients with high N/L ratio (39% vs 56%). Our results suggest that the N/L ratio is a predictor of progression of atherosclerosis.