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Clinical Specular Microscopy

1979; American Medical Association; Volume: 97; Issue: 9 Linguagem: Inglês

10.1001/archopht.1979.01020020288022

1538-3601

Ronald A. Laing,

Glaucoma and retinal disorders

• The clinical specular microscope shows the morphological appearance of the endothelium in normal and abnormal corneas. This instrument resolves the endothelial mosaic of the normal cornea into a quasiregular pattern of contiguous cells having well-defined cell boundaries. Cell size varies over a wide range in a number of disorders, and endothelial cells may assume shapes that are substantially different from their usual hexagonal appearance. Cell boundaries are dark and most commonly appear as a straight, narrow line. However, other types of cell boundaries, collectively referred to as doubled boundaries, have been encountered. Cell boundaries normally intersect in a manner that results in three angles of intersection, each approximately 60°, but variations from this pattern are seen. A number of noncellular structures also can be seen in the endothelial zone.