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Combination of π–π stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin

2011; Royal Society of Chemistry; Volume: 47; Issue: 40 Linguagem: Inglês

10.1039/c1cc14445f

1364-548X

Jinhua Liu, Jishan Li, Ying Jiang, Sheng Yang, Weihong Tan, Ronghua Yang,

Luminescence and Fluorescent Materials

On the basis of simultaneous electrostatic repulsion and π–π stacking interactions of carboxylic carbon nanoparticles (cCNPs) with single-stranded DNA, a noncovalent assembly of cCNPs and fluorescent aptamers is reported for rapid, sensitive, and selective detection of thrombin.