Blind signal separation from optical imaging recordings with extended spatial decorrelation
2000; Institute of Electrical and Electronics Engineers; Volume: 47; Issue: 5 Linguagem: Inglês
10.1109/10.841327
ISSN1558-2531
AutoresIngo Schießl, M. Stetter, J. E. W. Mayhew, Niall McLoughlin, J.S. Lund, Klaus Obermayer,
Tópico(s)Electrochemical Analysis and Applications
ResumoOptical imaging is the video recording of two-dimensional patterns of changes in light reflectance from cortical tissue evoked by stimulation. We derived a method, extended spatial decorrelation (ESD), that uses second-order statistics in space for separating the intrinsic signals into the stimulus related components and the nonspecific variations. The performance of ESD on model data is compared to independent component analysis algorithms using statistics of fourth and higher order. Robustness against sensor noise is scored. When applied to optical images, ESD separates the stimulus specific signal well from biological noise and artifacts.
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