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BIBTEX RIS

Tyrosinase-Inhibitory Long-Chain Esters from Amberboa ramosa

2005; Pharmaceutical Society of Japan; Volume: 53; Issue: 1 Linguagem: Inglês

10.1248/cpb.53.86

ISSN

1347-5223

Autores

Sher Bahadar Khan, Azhar-ul-Haq, Nighat Afza, Abdul Malik, Mahmud Khan, Muhammad Raza Shah, M. Iqbal Choudhary,

Tópico(s)

Natural product bioactivities and synthesis

Resumo

Long-chain esters 1 and 2 have been isolated from the chloroform-soluble fraction of Amberboa ramosa and their structures assigned to be methyl 2β(2S)-hydroxyl-7(E)-tritriacontenoate (1) and methyl 2β(2S)-O-β-D-galactopyranosyl-7(E)-tetratriacontenoate (2). In addition, tricontane (3) and apigenin (4) are also reported for the first time from this species. The structures were assigned on the basis of 1D and 2D NMR techniques. Compounds 1 and 2 showed strong to moderate inhibitory activity against tyrosinase.

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