Artigo Acesso aberto Revisado por pares

Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats

2015; BioMed Central; Volume: 16; Issue: S1 Linguagem: Inglês

10.1186/2050-6511-16-s1-a90

ISSN

2050-6511

Autores

Paul Stamm, Alexander Jabs, Matthias Oelze, Yuliya Mikhed, Swenja Kröller‐Schön, Philipp Welschof, Thomas Jansen, Michael Hausding, Maximilian Kopp, Sebastian Steven, Eberhard Schulz, JP Stasch, Thomas Münzel, Andreas Daiber,

Tópico(s)

Receptor Mechanisms and Signaling

Resumo

Figure 1 Aortic DHE fluorescence Effects of sGC activator BAY 60-2770 and sGC stimulator BAY 41-8543 in vivo treatment on oxidative stress parameters in tolerant rats.Quantification of vascular ROS formation in aortic cryo-sections was assessed by fluorescent microtopography using the superoxide-sensitive dye DHE (1

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