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Oral Amoxicillin Versus Benzyl Penicillin for Severe Pneumonia Among Kenyan Children: A Pragmatic Randomized Controlled Noninferiority Trial

2014; Oxford University Press; Volume: 60; Issue: 8 Linguagem: Inglês

10.1093/cid/ciu1166

1537-6591

Ambrose Agweyu, David Gathara, Jacquie Oliwa, Naomi Muinga, Tansy Edwards, Elizabeth Allen, Elizabeth Maleche‐Obimbo, Mike English, Florence Aweyo, Bernard Onyango Awuonda, Martin Chabi, Newton Isika, Mary Kariuki, Magdalene Kuria, Polycarp Mandi, Leah Masibo, Thaddeus Massawa, Wycliffe Mogoa, Beatrice Mutai, Gatwiri Muriithi, Samuel Ng'arng'ar, Rachel Nyamai, Dorothy Okello, Wilson Oywer, Lordin Wanjala,

Epilepsy research and treatment

Background. There are concerns that the evidence from studies showing noninferiority of oral amoxicillin to benzyl penicillin for severe pneumonia may not be generalizable to high-mortality settings.