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Pump-induced haemolysis: a comparison of short-term ventricular assist devices

2004; SAGE Publishing; Volume: 19; Issue: 2 Linguagem: Inglês

10.1191/0267659104pf729oa

1477-111X

Martin R. Bennett, Stephen Horton, Clarke A. Thuys, S Augustin, M Rosenberg, Christian P. Brizard,

Respiratory Support and Mechanisms

Centrifugal pumps are superior to roller pumps for extended support durations in terms of pump-induced haemolysis. In this study, we evaluated the commonly used Biomedicus BP 50 and compared it with the Jostra Rotaflow and a standard roller pump in an in vitro test circuit. Each circuit was run for a six-day period and repeated five times. Plasma haemoglobin values showed the roller pump to become more haemolytic than the Biomedicus ( p = 0.022) and the Rotaflow. A statistically significant difference between the Biomedicus and the Rotaflow was observed on day six of the trial ( p = 0.016), with the Rotaflow showing lower levels of haemolysis than the Biomedicus. These results support the use of the new generation centrifugal pump, the Rotaflow, as a suitable device for short-term ventricular assist.