Submicrometer Metallic Barcodes
2001; American Association for the Advancement of Science; Volume: 294; Issue: 5540 Linguagem: Inglês
10.1126/science.294.5540.137
ISSN1095-9203
AutoresSheila R. Nicewarner-Peña, Ronit Freeman, Brian D. Reiss, Lin He, David J. Peña, Ian D. Walton, R. CROMER, Christine D. Keating, Michael J. Natan,
Tópico(s)Nanofabrication and Lithography Techniques
ResumoWe synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.
Referência(s)