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DIFFUSION OF ANESTHETICS AND OTHER DRUGS THROUGH SILICONE RUBBER: THERAPEUTIC IMPLICATIONS*†

1968; Wiley; Volume: 30; Issue: 8 Series II Linguagem: Inglês

10.1111/j.2164-0947.1968.tb02565.x

2164-0947

Judah Folkman, Vernon H. Mark,

Medical History and Innovations

Transactions of the New York Academy of SciencesVolume 30, Issue 8 Series II p. 1187-1195 DIFFUSION OF ANESTHETICS AND OTHER DRUGS THROUGH SILICONE RUBBER: THERAPEUTIC IMPLICATIONS*† Judah Folkman M.D., Judah Folkman M.D. The Department of Surgery, Harvard Medical School The Sears Surgical Laboratory, Boston City Hospital Boston, Mass. Research Career Development Award 5K03 CA 28085–03 from the National Cancer Institute.Search for more papers by this authorVernon H. Mark M.D., Vernon H. Mark M.D. The Department of Surgery, Harvard Medical School The Sears Surgical Laboratory, Boston City Hospital Boston, Mass.Search for more papers by this author Judah Folkman M.D., Judah Folkman M.D. The Department of Surgery, Harvard Medical School The Sears Surgical Laboratory, Boston City Hospital Boston, Mass. Research Career Development Award 5K03 CA 28085–03 from the National Cancer Institute.Search for more papers by this authorVernon H. Mark M.D., Vernon H. Mark M.D. The Department of Surgery, Harvard Medical School The Sears Surgical Laboratory, Boston City Hospital Boston, Mass.Search for more papers by this author First published: June 1968 https://doi.org/10.1111/j.2164-0947.1968.tb02565.xCitations: 18 † This paper, illustrated with slides, was presented at a meeting of the Division on March 12, 1968. ‡ This work was supported by National Cancer Institute Grant CA 08185–03 and CA 07368–04. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Bass, P., R. A. Purdon & J. N. Wiley. 1965. Prolonged administration of atropine or histamine in a silicone rubber implant. Nature 208: 591. Bubb, B., V. H. Mark & W. H. Sweet. 1968. Intracerebral pharmacotherapy: Drug diffusion through silicone rubber chemodes. Nature (In press). Clifford, C. M., C. E. Yunker & M. D. Corwin. 1967. Control of the louse Polyplax serrata with systemic insecticides administered in silastic rubber implants. J. Econ. Entomol. 60: 1210. Dziuk, P. J. & B. Cook. 1966. Passage of steroids through silicone rubber. Endocrinology 78: 208. Folkman, J. & D. M. Long, Jr. 1964. The use of silicone rubber as a carrier for prolonged drug therapy. J. Surg. Res. 4: 139. Folkman, J., D. M. Long, Jr. & R. Rosenbaum. 1966. Silicone rubber: A new diffusion property useful for general anesthesia. Science 154: 148. Folkman, J., S. Winsey & T. Moghul. 1968a. Anesthesia by diffusion through silicone rubber. Anesthesiology 29: 410. Folkman, J., V. H. Mark, F. Ervin, K. Suematsu & R. Hagiwara. 1968b. Intracerebral gas anesthesia by diffusion through silicone rubber. Anesthesiology 29: 419. Powers, K. G. 1965. The use of silicone rubber implants for the sustained release of antimalarial and antischistosomal agents. J. Parasitol. 51 (Sect. 2): 53 (Abstr. 129). Segal, S. 1968. Sustained released hormonal preparation. I. Diffusion of various steroids through polymer membranes. (In press). Wilkinson, H. A. 1963. Intracranial Self-stimulation in Cats: A Study of The Neural Basis of Emotion. The Seeman Printery, Durham, N.C. Citing Literature Volume30, Issue8 Series IIJune 1968Pages 1187-1195 ReferencesRelatedInformation