Double metal-catalyzed cross-coupling reactions of alkenyl sulfoximines with diorganozinc reagents: Synthesis of optically active axial chiral allylic silanes
1992; Elsevier BV; Volume: 33; Issue: 4 Linguagem: Inglês
10.1016/s0040-4039(00)93968-6
ISSN1873-3581
AutoresHans‐Joachim Gais, Gred Bülow,
Tópico(s)Cyclopropane Reaction Mechanisms
ResumoNickel- and magnesium-catalyzed cross-coupling reaction of the alkenyl sulfoximine 5 with the pure diorganozinc reagents 6a and 6b gave the optically active allylic silanes 7a and 7b, respectively, Single metal catalysis was sufficient for the substitution of the bromide rac-9 whereas the sulfone rac-10 did neither under the conditions of single nor under that of double metal catalysis react with 6a.
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