Artigo Revisado por pares

Double metal-catalyzed cross-coupling reactions of alkenyl sulfoximines with diorganozinc reagents: Synthesis of optically active axial chiral allylic silanes

1992; Elsevier BV; Volume: 33; Issue: 4 Linguagem: Inglês

10.1016/s0040-4039(00)93968-6

ISSN

1873-3581

Autores

Hans‐Joachim Gais, Gred Bülow,

Tópico(s)

Cyclopropane Reaction Mechanisms

Resumo

Nickel- and magnesium-catalyzed cross-coupling reaction of the alkenyl sulfoximine 5 with the pure diorganozinc reagents 6a and 6b gave the optically active allylic silanes 7a and 7b, respectively, Single metal catalysis was sufficient for the substitution of the bromide rac-9 whereas the sulfone rac-10 did neither under the conditions of single nor under that of double metal catalysis react with 6a.

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