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Drug eruption reference manual 2001

2001; Elsevier BV; Volume: 45; Issue: 3 Linguagem: Inglês

10.1016/s0190-9622(01)70100-4

1097-6787

J. Graham Smith,

Pharmaceutical studies and practices

Drug eruption reference manual 2001Jerome Z. Litt, MD, Pearl River, New York, 2001, Parthenon Publishing Group. 600 pages. $149.00. Softcover.During 1 year of the 1990s, more than 100,000 hospitalized patients in the United States died from adverse drug reactions, and the number of outpatients who die annually must truly be staggering. An estimation of 200 to 500 reactions for each death hints at the enormous magnitude of the problem. This manual catalogs adverse drug reactions associated with more than 740 commonly prescribed generic and over-the-counter American medications. More than 4400 trade name drugs are listed.Drugs are categorized by class and, in an important change from the 2000 Manual, are indexed simultaneously with both trade and generic names. The drugs for the 100 most common reaction patterns are listed. There is also a new section on herbals, botanicals, trace elements, and supplements. Each drug is listed by generic name, synonym, trade name (with manufacturer), indications, uses, half-life, and major interactions with other drugs. Reactions of the skin, hair, nails, mucous membranes, and other systems are given. There are more than 18,000 references to journals and books, and 64 color plates are included.In this era of evidence-based medicine (EBM), this is probably the most anecdotal medical text extant. Does that detract? There is no reliable laboratory method for documenting that a drug has produced a reaction. Rechallenge is the “gold standard” for documentation of a drug reaction. But few of even the most dedicated EBMers would be willing to subject their patients routinely to this procedure.There is no book I refer to more frequently, an average of twice a day. In this day of polypharmacy, I often copy pages and give them to my patients to show them how their medications may be producing their problems. Every dermatologist and anyone (and that includes virtually all practitioners) who sees patients with adverse drug reactions should have access to this book. The complete information in the Manual is available on a CD-ROM for Windows and Macintosh platforms ($149). In addition, there is a 3.5-inch floppy disk for Windows that includes all the information minus the images ($75). Also new is a Palm OS version that contains all the information without the references and images ($45). A Web site (www.drugeruption.com), updated monthly, is also available ($98, purchased with the manual $50). Drug eruption reference manual 2001 Jerome Z. Litt, MD, Pearl River, New York, 2001, Parthenon Publishing Group. 600 pages. $149.00. Softcover. During 1 year of the 1990s, more than 100,000 hospitalized patients in the United States died from adverse drug reactions, and the number of outpatients who die annually must truly be staggering. An estimation of 200 to 500 reactions for each death hints at the enormous magnitude of the problem. This manual catalogs adverse drug reactions associated with more than 740 commonly prescribed generic and over-the-counter American medications. More than 4400 trade name drugs are listed. Drugs are categorized by class and, in an important change from the 2000 Manual, are indexed simultaneously with both trade and generic names. The drugs for the 100 most common reaction patterns are listed. There is also a new section on herbals, botanicals, trace elements, and supplements. Each drug is listed by generic name, synonym, trade name (with manufacturer), indications, uses, half-life, and major interactions with other drugs. Reactions of the skin, hair, nails, mucous membranes, and other systems are given. There are more than 18,000 references to journals and books, and 64 color plates are included. In this era of evidence-based medicine (EBM), this is probably the most anecdotal medical text extant. Does that detract? There is no reliable laboratory method for documenting that a drug has produced a reaction. Rechallenge is the “gold standard” for documentation of a drug reaction. But few of even the most dedicated EBMers would be willing to subject their patients routinely to this procedure. There is no book I refer to more frequently, an average of twice a day. In this day of polypharmacy, I often copy pages and give them to my patients to show them how their medications may be producing their problems. Every dermatologist and anyone (and that includes virtually all practitioners) who sees patients with adverse drug reactions should have access to this book. The complete information in the Manual is available on a CD-ROM for Windows and Macintosh platforms ($149). In addition, there is a 3.5-inch floppy disk for Windows that includes all the information minus the images ($75). Also new is a Palm OS version that contains all the information without the references and images ($45). A Web site (www.drugeruption.com), updated monthly, is also available ($98, purchased with the manual $50).