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Clandestine drug synthesis

1986; Wiley; Volume: 6; Issue: 1 Linguagem: Inglês

10.1002/med.2610060103

ISSN

1098-1128

Autores

William H. Soine,

Tópico(s)

Attention Deficit Hyperactivity Disorder

Resumo

Medicinal Research ReviewsVolume 6, Issue 1 p. 41-74 Article Clandestine drug synthesis William H. Soine, William H. Soine Department of Medicinal Chemistry, School of Pharmacy, Medical College of Virginia/Virginia Commonwealth University, Richmond, Virginia 23298Search for more papers by this author William H. Soine, William H. Soine Department of Medicinal Chemistry, School of Pharmacy, Medical College of Virginia/Virginia Commonwealth University, Richmond, Virginia 23298Search for more papers by this author First published: January/March 1986 https://doi.org/10.1002/med.2610060103Citations: 42AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 J. W. Gunn, Jr., J. For. Sci., 13, 302 (1968). 2 J. W. Gunn, Jr., D. W. Johnson and W. P. Butler, J. For. Sci., 15, 51 (1970). 3 R. S. Frank, J. For. Sci., 28, 18 (1983). 4 A. T. Shulgin, Clin. Tox., 8, 405 (1975). 5 Anonymous, Bull. Narc., 9, 27 (1953). 6 D. W. Johnson and J. W. Gunn, Jr., J. For. Sci., 17, 629 (1972). 7 L. F. Small and R. E. Lutz, Chemistry of the Opium Alkaloids, U. S. Government Printing Office: Washington, D. C., 1932, pp. 153–154. 8 G. K. Bhattacharyya and R. A. Johnson, Statistical Concepts and Methods, Wiley, New York, 1977, p. 31. 9 F. Van Vendeloo, J. P. Franke and R. A. DeZeeuw, Pharm. Weekl., 2, 1397 (1980). 10 H. Huizer, H. Logtenberg, A. J. Steenstra, Bull. Narc., 29, 65 (1977). 11 H. Lim and S. Chow, J. For. Sci., 23, 319 (1978). 12 C. C. Clark, Microgram, 11, 5 (1978). 13 P. J. Twitchett, J. Chromatogr., 104, 205 (1975). 14 E. P. J. Vander Slooten and H. J. Vander Helm, For. Sci., 6, 83 (1975). 15 D. Bernhauer and E. F. Fuchs, Arch-Kriminol., 5, 73 (1982). 16 P. J. O'Neil, P. B. Baker and T. A. Gough, J. For. Sci., 29, 889 (1984). 17 P. G. Vincent and B. F. Engelke, J. Ass. Off. Anal. Chem., 62, 310 (1979). 18 K. Narayanaswami, H. C. Golani and R. D. Dua, For. Sci. Int., 14, 181 (1979). 19 C. T. VanMeter, Remington's Pharmaceutical Sciences, 13th ed., E. W. Martin, Ed., Mack Publishing Co.: Easton, Pa., 1965, pp. 824–825. 20 G. R. Nakamura and T. Ukita, J. For. Sci., 7, 465 (1962). 21 G. R. Nakamura and H. J. Meuron, Anal. Chem., 41, 1124 (1969). 22 G. Bohn, E. Schulte and W. Audick, Arch. F. Kriminol., 160, 27 (1977). 23 J. D. Wittwer, Jr., For. Sci. Int., 18, 215 (1981). 24 F. Mari, Bull. Narc., 34, 37 (1982). 25 M. Gloger and H. Neumann, For. Sci. Int., 22, 63 (1983). 26 The Merck Index, 9th ed., M. Windholz, Ed., Merck and Co., Inc., Rahway, N. J., 1976, p. 316. 27 J. H. Jaffe and W. R. Martin, in The Pharmacological Basis of Therapeutics, 6th ed., A. G. Gilman, L. S. Goodman and A. Gilman, Eds., MacMillan Publishing Co., Inc., New York, 1980, p. 496. 28 J. D. Wittwer, Jr., J. For. Sci., 18, 138 (1973). 29 V. Hodge, Microgram, 8, 45 (1975). 30 I. S. Lurie, S. M. Sottolano and S. Blasof, J. For. Sci., 27, 519 (1982). 31 L. F. Small and R. E. Lutz, Chemistry of the Opium Alkaloids, U. S. Government Printing Office, Washington, D. C., 1932, p. 294. 32 C. B. Teer, Microgram, 11, 102 (1978). 33 J. M. Moore, A. C. Allen and D. A. Cooper, Anal. Chem., 56, 642 (1984). 34 L. F. Small, N. B. Eddy, E. Mosettig and C. K. Himmelsbach, Studies on Drug Addiction, U. S. Government Printing Office, Washington, D. C., 1938, pp. 1–36. 35 J. G. Umans and C. E. Inturrisi, J. Pharm. Exp. Ther., 218, 409 (1981). 36 O. Lockridge, N. Mottershaw-Jackson, H. W. Eckerson and B. N. LaDu, J. Pharm. Exp. Ther., 215, 1 (1980) and references therein. 37 E. R. Garrett and T. Gurkan, J. Pharm. Sci., 69, 1116 (1980). 38 Physicians Desk Reference, 37th ed., B. B. Huff, ed., Medical Economics Co., Oradell, N. J., 1983, p. 1680–1681. 39 AMA Drug Evaluations, 3rd ed., PSG Publishing Co., Inc., Littleton, MA., 1977, pp. 329–330. 40 M. Nickerson in The Pharmacological Basis of Therapeutics, 4th ed., L. S. Goodman and A. Gilman, Eds., The MacMillan Co., London, 1970, pp. 753–754. 41 N. D. Vaziri, J. Stokes, and T. R. Treadwell, Clin. Tox., 18, 417 (1981). 42 W. Wirth, R. Gosswald, K. L. H. Risse and U. Horlein, Arch. Int. Pharmacodyn., 151, 515 (1964). 43 N. B. Eddy, H. Friebel, K.-J. Hahn and H. Halbach in Codeine and Its Alternates for Pain and Cough Relief, World Health Organization, Geneva, Switzerland, 1970, pp. 178–184. 44 W. A. Lieb and H. J. Scherf, Klin. Monatsbl. Augenheilk. 128, 686 (1956), Chem. Abstr., 54, 11271f (1960). 45 G. R. Nakamura, Clin. Tox., 13, 75 (1978). 46 M. H. Greene, Am. J. Drug Alcohol Abuse, 2, 141 (1975). 47 E. L. Zimney and J. L. Luke, J. For. Sci., 26, 462 (1981). 48 D. P. Desmond, J. F. Maddux and A. Trevino, Am. J. Drug Alcohol Abuse, 5, 39 (1978). 49 G. C. Davis, A. C. Williams, S. P. Markey, M. H. Ebert, E. D. Caine, C. M. Reichert and I. J. Kopin, Psych. Res., 1, 249 (1979). 50 J. W. Langston, P. Ballard, J. W. Tetrud and I. Irwin, Science, 219, 979 (1983). 51 A. Ziering, L. Berger, S. D. Heineman and J. Lee, J. Org. Chem., 12, 894 (1947). 52 J. Buchi, M. Prost, H. Eichenberger and R. Lieberherr, Helv. Chim. Acta, 35, 1527 (1952). 53 J. Buchi and M. Prost, Ann. Pharm. Fran., 12, 241 (1954). 54 R. S. Burns, C. C. Chiueh, S. Markey, M. H. Ebert, D. Jacobowitz and J. J. Kopin, Proc. Nat. Acad. Sci., USA, 80, 4546 (1983). 55 J. W. Langston, L. S. Forno, C. S. Rebert and I. Irwin, Brain Res., 292, 390 (1984). 56 Anonymous, Microgram, 16, 217 (1983). 57 D. Lednicer and L. Mitscher, The Organic Chemistry of Drug Synthesis, John Wiley and Sons, New York, 1977, p. 310. 58 M. Janssen, Janssen Pharmaceutica, personnel communication, 1984. 59 T. C. Kram, D. A. Cooper and A. C. Allen, Anal. Chem., 53, 1379A (1981). 60 D. Cooper, A. Allen and I. Lurie, Microgram, 14, 154 (1981). 61 Anonymous, Microgram, 16, 147 (1983). 62 J. A. Heagy, Microgram, 14, 61 (1981). 63 T. J. Gillespie, A. J. Gandolfi, T. P. Davis and R. A. Morano, J. Anal. Tox., 6, 139 (1982). 64 J. H. Jaffee and W. R. Martin, in The Pharmacological Basis of Therapeutics, 6th ed., A. G. Gilman, L. S. Goodman and A. Gilman, Eds., MacMillan Publishing Co., Inc., New York, 1980, p. 518. 65 P. A. J. Janssen and C. A. M. van der Eycken in Drugs Affecting the Central Nervous System, Vol. 2, A. Burger, Ed., Marcel Dekker, New York, 1968, pp. 51–54. 66 M. D. Aceto, L. S. Harris and E. L. May in Problems of Drug Dependence, 1981, NIDA Research Monograph 41, Washington, D. C., U. S. Government Printing Office, 1982, p. 338. 67 A. Sinnema and A. M. A. Verweij, Bull. Narc., 23, 37 (1981). 68 S. Young, J. Chem. Soc., 59, 621 (1891). 69 T. C. Kram, J. Pharm. Sci., 66, 443 (1977). 70 M. L. Moore, Organic Reactions, 5, 315 (1949). 71 J. N. Lomonte, W. T. Lowry and I. C. Stone, J. For. Sci., 21, 575 (1976). 72 T. C. Kram, J. For. Sci., 24, 596 (1979). 73 A. M. Vander Ark, I. A. Sinnema, J. M. Vander Toorn and A. M. A. Verweij, Pharm. Weekblad, 113, 341, (1981). 74 A. M. Vander Ark, I. A. Sinnema, A. B. E. Theeuwen, J. M. Vander Toorn and A. M. A. Verwey, Pharm. Weekblad, 113, 41 (1978). 75 A. M. Vander Ark, A. M. A. Verweij and A. Sinnema, J. For. Sci., 23, 693 (1978). 76 A. M. Vander Ark, A. B. E. Theeuwen and A. M. A. Verweij, Pharm. Weekblad., 112, 977 (1977). 77 A. M. Vander Ark, A. Sinnema, J. M. Vander Toorn and A. M. A. Verweij, Pharm. Weekblad, 112, 980 (1977). 78 A. B. E. Theeuwen and A. M. A. Verweij, For. Sci. Int., 15, 237 (1980). 79 A. B. E. Theeuwen and A. M. A. Verweij, Archiv, Krimin., 168, 23 (1981). 80 B. H. G. Wassink, A. Diujndam and A. C. A. Jansen, J. Chem. Ed., 51, 671, (1974). 81 D. Cooper, Microgram, 12, 108 (1979). 82 T. C. Kram and A. V. Kruegel, J. For. Sci., 22, 842 (1976). 83 M. LeBelle, M. Sileika and M. Romach, J. Pharm. Sci., 62, 862 (1983). 84 R. P. Barron, A. V. Kruegel, J. M. Moore and T. C. Kram, J. Assoc. Off. Anal. Chem., 57, 1147 (1974). 85 K. Bailey, J. G. Boulanger, D. Legault and S. Taillefer, J. Pharm. Sci., 63, 1575 (1974). 86 C. B. Teer and J. B. Wittwer, Microgram, 14, 99 (1981). 87 Anonymous, Microgram, 15, 188 (1982). 88 J. J. Alvarez and B. R. Goldston, Microgram, 12, 125 (1979). 89 A. W. Davidson, Microgram, 16, 142 (1983). 90 R. Gelsomino and D. Robak, Microgram, 9, 77 (1976). 91 Anonymous, Microgram, 13, 190 (1980). 92 Anonymous, Microgram, 12, 96 (1979). 93 K. Bailey, H. D. Beckstead, D. Legault and D. Verner, J. Ass. Off. Anal. Chem., 57, 1134 (1974). 94 Anonymous, Microgram, 6, 80 (1973). 95 Anonymous, Microgram, 6, 140 (1973). 96 Use and Abuse of Amphetamine and Its Substitutes, J. V. Spotts and C. A. Spotts, Eds., U. S. Department of Health, Education and Welfare Research Issue 25, U. S. Printing Office, Washington, D. C., 1980. 97 T. Kojima, I. Une, M. Yashiki, J. Noda, K. Sakai and K. Yamamoto, For. Sci. Int., 24, 87 (1984). 98 C. R. Schuster in Handbook of Experimental Pharmacology, Psychotropic Agents, Part III: Alcohol and Psychotomimetics-Psychotropic Effects of Central Acting Drugs, Vol. 55; F. Hoffmeister and G. Stille, Eds., Springer-Verlag, New York, 1982, pp 587–605. 99 E. E. Swanson, C. C. Scott, H. M. Lee and K. K. Chem, J. Pharm. Exp. Ther., 79, 329 (1943). 100 J. H. Biel and B. A. Bopp, Handbook of Psychopharmacology, Stimulants, Vol 3, L. L. Iverson, S. D. Iverson and S. H. Snyder, Eds. Plenum Press, New York, 1978, p. 14. 101 L. S. Goodman and A. Gilman, The Pharmacological Basis of Therapeutics, 2nd ed., Macmillan Company, New York, 1956, pp. 532–533. 102 K. M. Taylor and S. H. Snyder, Science, 168, 1487 (1970). 103 L. W. Roth, R. K. Richards, I. Shemano and B. B. Morphis, Arch. Int. Pharmcodyn., 98, 362 (1954). 104 C. J. Cavallito and A. P. Gray, U. S. Patent 3, 489, 840 (1970), Chem. Abstr. 72, 90091u (1970). 105 A. Ogata and S. Niiobu, J. Pharm. Soc. Japan, 62, 152 (1942), Chem. Abstr. 45, 1728d (1954). 106 D. E. Moisset de Espanes and B. Weksler, Rev. Soc. Argentina Biol., 29, 195 (1953). 107 J. Hano and W. Wojewodzki, Arch. Immunol. Terapii Doswiadczalnej, 9, 7 (1961), Chem. Abstr. 59, 15769f (1963). 108 C. K. Nielsen, M. P. Magnussen, E. Kampmann and H.-H. Frey, Arch. Int. Pharmacodyn., 170, 428 (1967). 109 Anonymous, Microgram, 14, 165 (1981). 110 C. F. Barfknecht, R. V. Smith, D. E. Nichols, J. L. Leseney, J. P. Long and J. A. Engelbrecht, J. Pharm. Sci., 60, 799 (1971). 111 J. H. Biel and B. A. Bopp in Handbook of Psychopharmacology, Stimulants, Vol. 11, L. L. Iverson, S. D. Iverson and S. H. Snyder, Eds., Plenum Press, New York, 1978, pp. 1–39. 112 A. H. Beckett and L. G. Brookes in International Symposium on Amphetamines and Related Compounds, E. Costa and S. Garattini Eds., Raven Press, New York, 1970, pp. 109–139. 113 T. B. Vree and J. M. vanRossum in International Symposium on Amphetamines and Related Compounds, E. Costa and S. Garattini Eds., Raven Press, New York, 1970, pp. 165–190. 114 A. T. Shulgin in Handbook of Psychopharmacology, Stimulants, Vol. 11, L. L. Iverson, S. D. Iverson and S. H. Snyder Eds., Plenum Press, New York, 1978, pp. 243–333. 115 E. P. Claus, V. E. Tyler and L. R. Brady, Pharmacognosy, 6th ed., Lea and Febiger, Philadelphia, PA, 1970, pp. 240–242. 116 J. M. Moore, J. Ass. Off. Anal. Chem., 56, 1199 (1973). 117 J. M. Moore, J. Chromatogr., 101, 215 (1974). 118 T. Lukaszewski and W. K. Jeffery, J. For. Sci., 25, 499 (1980). 119 J. M. Moore, The Application of Derivitization Techniques in Forensic Drug Analysis, Proceedings of the International Symposium and Instrumental Applications in Forensic Drug Chemistry, May 29–30; U. S. Government Printing Office, Washington, D. C., pp. 180–201. 120 C. C. Clark, Microgram, 11, 184 (1978). 121 I. Jane, A. Scott, R. W. L. Sharpe and P. C. White, J. Chromatogr., 214, 243 (1981). 122 F. T. Noggle and C. R. Clark, J. Ass. Off. Anal. Chem., 65, 756 (1982). 123 C. C. Clark, Microgram, 16, 25 (1983). 124 Anonymous, Microgram, 14, 90 (1981). 125 F. Medina, Microgram, 12, 139 (1979). 126 C. C. Clark, Microgram, 14, 136 (1981). 127 R. Willstatter, O. Wolfes and R. Madder, Ann., 434, 111 (1923). 128 J. H. Jaffe in The Pharmacological Basis of Therapeutics, 6th ed., A. G. Gilman, L. S. Goodman and A. Gilman, Eds., MacMillan Publishing Co., Inc., New York, NY, 1980, pp. 554–556. 129 R. Hawks in Cocaine, 1977, R. C. Petersen and R. C. Stillman, Eds., National Institute of Drug Abuse Research Monograph #13; U. S. Printing Office, Washington, D. C., 1977, pp. 47–61. 130 A. L. Misra, P. K. Nayak, R. Bloch and S. J. Mule, J. Pharm. Pharmac., 27, 784 (1975). 131 M. L. McKenna, B. T. Ho and L. F. Englert, Pharm. Biochem. Behav., 10, 273 (1979). 132 J. C. Valentour, V. Aggarwal, M. P. McGee and S. W. Goza, J. Anal. Tox., 2, 134 (1978). 133 A. P. Chadbourne, Brit. Med. J., 2, 402 (1892). 134 A. T. Shulgin, T. Sargent and C. Naranjo, Nature, 221, 537 (1969). 135 Anonymous, Microgram, 6, 66 (1973). 136 Anonymous, Microgram, 3, 105 (1970). 137 A. T. Shulgin, J. Psychedelic Drugs, 8, 169 (1976). 138 Anonymous, Microgram, 5, 84 (1972). 139 Anonymous, Microgram, 1, 1 (1967). 140 A. T. Shulgin, T. Sargent and C. Naranjo, Pharm., 5, 103 (1971). 141 D. Delliou, For. Sci. Int., 21, 259 (1983). 142 A. T. Shulgin and M. F. Carter, Psychopharmacol. Commun., 1, 93 (1975). 143 Anonymous, Microgram, 12, 1 (1979). 144 S. H. Snyder, L. A. Faillace and H. Weingartner, Arch. Gen. Psychiat., 21, 95 (1969). 145 Anonymous, Microgram, 12, 197 (1979). 146 C. Naranjo, A. T. Shulgin and T. Sargent, Med. Pharmacol. Exp., 17, 359 (1967). 147 T. R. Gaston and G. T. Rasmussen, Microgram, 4, 60 (1972). 148 Anonymous, Microgram, 7, 28 (1974). 149 Anonymous, Microgram, 13, 32 (1980). 150 J. A. Heagy, Microgram, 9, 102 (1976). 151 M. U. Tsao, J. Am. Chem. Soc., 73, 5495 (1951). 152 D. E. Nichols, J. Pharm. Sci., 70, 839 (1981). 153 D. E. Nichols and R. A. Glennon, In Hallucinogens: Neurochemical, Behavioral and Clinical Perspectives, B. L. Jacobs Ed., Raven Press, New York, 1983 or 1984. 154 R. A. Glennon, in Psychopharmacology, D. F. Smith, Ed., CRC Press, Boca Raton, 1983, pp. 327–368. 155 C. L. Winek, W. D. Collom and J. D. Bricker, Clin. Tox., 18, 267 (1981). 156 T. Lukaszewski, Clin. Tox., 15, 409 (1979). 157 A. Polks, M. A. Mackell and W. K. Drake, J. For. Sci., 24, 70 (1979). 158 P. N. Thiessen and D. A. Cook, Clin. Tox., 6, 45 (1973). 159 Anonymous, Microgram, 15, 11 (1982). 160 Anonymous, Microgram, 12, 158 (1979). 161 J. S. Cowie, A. L. Holtham and L. V. Jones, J. Forensic Sci., 27, 527 (1982). 162 M. E. Speeter and W. C. Anthony, J. Am. Chem. Soc., 76, 6208 (1954). 163 G. Stork and R. K. Hill, J. Am. Chem. Soc., 76, 6209 (1957). 164 Anonymous, Microgram, 3, 108 (1970). 165 Anonymous, Microgram, 4, 26 (1971). 166 Anonymous, Microgram, 6, 33 (1973). 167 D. L. Crookes, K. P. Parry and G. F. Smith, Pol. J. Chem., 53, 73 (1979). 168 A. T. Shulgin and D. E. Nichols in The Psychopharmacology of Hallucinogens; Pergamon Press, New York, 1978, pp. 74–83. 169 R. A. Glennon and J. A. Rosecrans, Neurosci. Biobehav. Rev., 6, 489 (1982). 170 R. R. Hunt and R. W. Brimblecombe, J. Med. Chem., 10, 646 (1967). 171 R. G. Taborsky, P. Delvigs, I. H. Page and N. Crawford, J. Med. Chem., 8, 460 (1965). 172 W. C. Anthony and J. Szmuszkovicz, U. S. Pat. 2,821,532 (1958) from Chem. Abst. 52, 10203d (1958). 173 W. L. Garbrecht, J. Org. Chem., 24, 368 (1959). 174 A. B. Clark, Microgram., 6, 37 (1973). 175 W. I. Taylor, Indole Alkaloids, Pergamon Press, London, 1966, pp. 48–51. 176 P. McDonald, C. F. Martin, D. J. Woods, P. B. Baker and T. A. Gough, J. For. Sci., 29, 120 (1984). 177 D. V. Sankar, LSD-A Total Study, Westbury, N. Y., PJD Publications, 1975. 178 H. Isbell, E. J. Miner and C. R. Logan, Psychopharm., 1, 20 (1959). 179 Phencyclidine (PCP) Abuse: An Appraisal, Ed. R. C. Petersen and R. C. Stillman, NIDA Research Monograph 21, U. S. Government Printing Office, Washington, D. C., 1978. 180 V. H. Maddox, E. F. Godefroi and R. F. Parcell, J. Med. Chem., 8, 230 (1965). 181 A. Kalir, H. Edery, Z. Pelah, D. Balderman and G. Porath, J. Med. Chem., 12, 473 (1969). 182 A. T. Shulgin and D. E. MacLean, Clin. Tox., 9, 553 (1976). 183 G. R. Nakamura, E. C. Griesemer, L. E. Joiner and T. T. Noguchi, Clin. Tox., 14, 383 (1979). 184 J. A. Heagy, Microgram, 5, 122 (1972). 185 Anonymous, Microgram, 8, 27 (1975). 186 R. D. Budd, New Eng. J. Med., 303, 588 (1980). 187 A. B. Clark, Microgram, 11, 59 (1978). 188 E. R. Thompson and T. A. McCleary, Microgram, 13, 194 (1980). 189 W. H. Soine, R. L. Balster, K. E. Berglund, C. D. Martin and D. T. Agee, J. Anal. Tox., 6, 41 (1982). 190 K. Bailey, J. Pharm. Sci., 76, 885 (1978). 191 J. E. Smialek, J. R. Monforte, R. Gault and W. V. Spitz, J. Anal. Tox., 3, 209 (1979). 192 Anonymous, Microgram, 12, 22 (1979). 193 W. M. Davis, R. F. Borne, R. B. Hackett and I. W. Waters, Life Sci., 26, 2105 (1980). 194 W. H. Soine, W. C. Vincek, D. T. Agee, J. Boni, G. C. Burley, T. H. Casey, M. Christian, A. Jones, D. T. King, D. Martin, D. J. O'Neil, P. E. Quinn and P. Strother, J. Anal. Tox., 4, 217 (1980). 195 D. T. Agee, Bureau of Forensic Science, Division of Consolidated Laboratory Sciences, Commonwealth of Virginia, personal communication, 1982. 196 R. D. Porter, Microgram, 8, 151 (1975). 197 D. C. Perry, Clin. Toxicol., 9, 339 (1975). 198 K. Bailey, A. Y. K. Chow, R. H. Downie and R. K. Pike, J. Pharm. Pharmac., 28, 713 (1976). 199 H. G. Giles, K. L. Adamson, J. A. Marshman and E. M. Sellers, Can. J. Pharm. Sci., 12, 107 (1977). 200 J. R. Ballinger and J. A. Marshman, J. Anal. Tox., 3, 158 (1979). 201 E. J. Cone, D. B. Vaupel and W. F. Buchwald, J. Anal. Tox., 4, 119 (1980). 202 J. K. Baker, Anal. Chem., 54, 347 (1982). 203 C. Helisten and A. T. Shulgin, J. Chromatogr., 117, 232 (1976). 204 W. H. Soine, K. T. Brady, R. L. Balster, and J. Q. Underwood, Res. Comm. Chem. Path. Pharm., 30, 59 (1980). 205 V. A. Folen, Microgram, 6, 22 (1973). 206 L. A. Jones, R. W. Beaver, T. L. Schmoeger, J. F. Ort and J. D. Leander, J. Org. Chem., 46, 3330 (1981). 207 L. A. Jones, R. W. Beaver and T. L. Schmoeger, Anal. Chem., 54, 182 (1982). 208 E. J. Cone, R. L. McQuinn and H. E. Shannon, J. Pharm. Exp. Ther., 228, 147 (1984) and references therein. 209 A. Kalir, Psychopharm. Bull., 16, 54 (1980). 210 A. Allen, S. Carr, D. Cooper, E. Franzosa, J. Koles, T. Kram and E. Solon, Microgram, 13, 32, 44, (1980). 211 J. Taillades and A. Commeyras, Tetrahedron, 30, 127 (1974). 212 R. G. H. Baumeister, H. Schievelbein and G. Zickgraf-Rudel, Arzneim. Forsch., 25, 1056 (1975). 213 J. C. Linnell, J. Wilson, R. F. Crampton, W. T. Smith, J. F. Knowles, I. F. Gaunt, I. J. Wise, and D. M. Matthews, Toxicology, 14, 81 (1979). 214 P. K. Gupta, W. H. Lawrence, J. E. Turner and J. Autien, Tox. Appl. Pharmacol., 49, 525 (1979). 215 D. C. Tasher, L. G. Abood, F. A. Gibbs and E. L. Gibbs, J. Neuropsy., 1, 266 (1960). 216 Y. Okano, T. Miyata, S.-H. Hung, T. Motoya, M. Kataoka, K. Takahama and Y. Kase, Japan. J. Pharmacol., 28, 41 (1978) and references therein. 217 B. R. Martin and A. S. Freeman, Fed. Proc., 42, 2561 (1983). 218 W. J. Freed, D. R. Weinberger, L. A. Bing and R. J. Wyatt, Psychopharm., 71, 291 (1980). 219 D. Legault, J. Chrom. Sci., 20, 228 (1982) and references therein. 220 A. S. Freeman and B. R. Martin, J. Pharm. Sci., 70, 1002 (1981). 221 C. E. Cook, D. R. Brine, G. D. Quin, M. Perez-Reyes and S. R. DiGuiseppi, Clin. Pharm. Ther., 31, 635 (1982) and references therein. 222 B. R. Martin, B. B. Bailey, H. Awaya, E. L. May and N. Narasimhachari, Drug Metab. Disp., 10, 685 (1982). 223 M. P. Holsapple, A. E. Munson, A. S. Freeman and B. R. Martin, Life Sci., 31, 803 (1982). 224 J. D. Leander, J. F. Ort and L. A. Jones, Res. Comm. Sub. Abuse, 2, 173 (1981). 225 Anonymous, Microgram, 6, 183 (1973). 226 P. Daenens and M. VanBoven, J. For. Sci., 21, 552 (1976). 227 Anonymous, Microgram, 13, 190 (1980). 228 T. A. DalCason, S. A. Angelos and O. Washington, J. For. Sci., 26, 793 (1981). 229 Martindale The Extra Pharmacopeia, 28th ed., J. E. F. Reynolds, Ed., The Pharmaceutical Press, London, 1982, p. 805. 230 Anonymous, Microgram, 14, 67 (1981). 231 P. Lorimer, Microgram, 17, 72 (1984). 232 W. O. Kiser, Microgram, 17, 75 (1984). 233 K. M. McGuinness, Microgram, 14, 161 (1981). 234 Anonymous, Microgram, 8, 61 (1975). 235 Anonymous, Microgram, 10, 2 (1977). 236 Anonymous, Microgram, 10, 134 (1977). 237 J. A. Ostrenga, Clin. Tax., 6, 607 (1973). 238 J.-R. Boissier, C. Dumont and R. Ratouis, Therapie, 2, 9 (1967). 239 M. L. Gujral, P. N. Saxena and R. S. Tiwar, Ind. J. Med. Res., 43, 637 (1955). 240 M. L. Gujral, P. N. Saxena and R. S. Tiwar, Ind. J. Med. Sci., 10, 877 (1956). 241 E. K. Weisburger, A. B. Russfield, F. Homburger, J. H. Weisburger, E. Boger, C. G. VanDongen, K. C. Chu, J. Env. Path. Tox., 2, 325 (1982). 242 G. F. Rubino, G. Scansetti, G. Piolatto and E. Pira, Environ. Res., 27, 241 (1982). Citing Literature Volume6, Issue1January/March 1986Pages 41-74 ReferencesRelatedInformation

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