Artigo Acesso aberto Revisado por pares

Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys

2013; American Association for the Advancement of Science; Volume: 5; Issue: 194 Linguagem: Inglês

10.1126/scitranslmed.3005795

ISSN

1946-6242

Autores

Federico Mingozzi, Xavier M. Anguela, Giulia Pavani, Yifeng Chen, Robert J. Davidson, Daniel J. Hui, Mustafa N. Yazicioglu, Liron Elkouby, Christian Hinderer, Armida Faella, Carolann Howard, Alex Tai, Gregory M. Podsakoff, Shangzhen Zhou, Etiena Basner‐Tschakarjan, J. Fraser Wright, Katherine A. High,

Tópico(s)

RNA Interference and Gene Delivery

Resumo

Capsid decoys enhance the efficacy of AAV vector transduction after systemic delivery in the presence of neutralizing antibodies.

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