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The Effects of Increased Penetration of Betamethasone Dipropionate in a Propylene Glycol Base (Diprolene) for Psoriasis

1981; SAGE Publishing; Volume: 9; Issue: 2 Linguagem: Inglês

10.1177/030006058100900208

1473-2300

Aleksej Kansky,

Pharmaceutical studies and practices

The efficacy and safety of betamethasone dipropionate, 0.05% in a propylene glycol base (Diprolene), was investigated in an open, fixed-dose study of thirty-one patients with resistant psoriasis. Clearing of lesions or marked improvement occurred in 97% (thirty out of thirty-one) of patients. Increased penetration of corticosteroid did not cause adrenal suppression or other adverse reactions.