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Long-Acting Parenteral Nanoformulated Antiretroviral Therapy: Interest and Attitudes of HIV-Infected Patients

2013; Future Medicine; Volume: 8; Issue: 11 Linguagem: Inglês

10.2217/nnm.12.214

1748-6963

Jennifer Williams, Harlan Sayles, Jane L. Meza, Patrick Sayre, Uriel Sandkovsky, Howard E. Gendelman, Charles Flexner, Susan Swindells,

HIV Research and Treatment

Aim: To gauge patient interest in receiving long-acting injectable nanoformulated antiretroviral therapy. Methods: Four hundred adult HIV-infected patients currently prescribed antiretroviral therapy were surveyed. χ2 tests were used for comparisons of interest across groups. Results: Respondents were 68% male and 53% African–American, with a mean age of 47 years. Overall, 73% of patients indicated that they would definitely or probably try injectable nanoformulated antiretroviral therapy; 61% with weekly dosing; 72% every 2 weekly; and 84% monthly. In total, 48% indicated that they were very concerned about the possible side effects and 35% were very concerned about needle use. Conclusion: The majority of respondents indicated that they definitely or probably would try parenteral nanoformulated antiretroviral therapy. Original submitted 24 May 2012; Revised submitted 2 November 2012; Published online 23 April 2013