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BIBTEX RIS

Ventilatory and Metabolic Compensation in Dogs With Acid‐Base Disturbances

1991; Wiley; Volume: 1; Issue: 2 Linguagem: Inglês

10.1111/j.1476-4431.1991.tb00015.x

1479-3261

Helio S. Autran de Morais, Stephen P. DiBartola,

Respiratory Support and Mechanisms

Summary Ventilatory and metabolic compensation to acid‐base disturbances is reviewed. The mechanisms for compensation as well as the values obtained from several studies using normal dogs and dogs with experimentally induced diseases are provided. Compensation is not the same in dogs and human beings. Dogs have a better ability to adapt to most respiratory disorders, and human beings adapt better to metabolic acidosis. In metabolic alkalosis and chronic respiratory acidosis there is no difference in compensation between these species. Ventilatory compensation for metabolic disorders in dogs is the same whether they have metabolic acidosis or metabolic alkalosis, whereas metabolic compensation in respiratory disturbances is less effective in acidosis. Values for the expected changes in PCO 2 in dogs with metabolic acidosis and metabolic alkalosis, and for bicarbonate concentration (HCO 3 ‐) in dogs with acute and chronic respiratory alkalosis and acidosis are presented.