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Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging

2006; Optica Publishing Group; Volume: 14; Issue: 8 Linguagem: Inglês

10.1364/oe.14.003354

1094-4087

Daniel X. Hammer, R. Daniel Ferguson, Chad E. Bigelow, Nicusor Iftimia, Teoman E. Ustun, Stephen A. Burns,

Corneal surgery and disorders

A retinal imaging instrument that integrates adaptive optics (AO), scanning laser ophthalmoscopy (SLO), and retinal tracking components was built and tested. The system uses a Hartmann-Shack wave-front sensor (HS-WS) and MEMS-based deformable mirror (DM) for AO-correction of high-resolution, confocal SLO images. The system includes a wide-field line-scanning laser ophthalmoscope for easy orientation of the high-magnification SLO raster. The AO system corrected ocular aberrations to <0.1 mum RMS wave-front error. An active retinal tracking with custom processing board sensed and corrected eye motion with a bandwidth exceeding 1 kHz. We demonstrate tracking accuracy down to 6 mum RMS for some subjects (typically performance: 10-15 mum RMS). The system has the potential to become an important tool to clinicians and researchers for vision studies and the early detection and treatment of retinal diseases.