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In vivo assessment and visualization of intracranial arterial hemodynamics with flow-sensitized 4D MR imaging at 3T.

2007; American Society of Neuroradiology; Volume: 28; Issue: 3 Linguagem: Inglês

1936-959X

Stephan G. Wetzel, Stephan Meckel, Alex Frydrychowicz, Leo H. Bonati, Ernst‐Wilhelm Radue, Klaus Scheffler, Jürgen Hennig, Michael Markl,

Cardiovascular Health and Disease Prevention

SUMMARY: We evaluated electrocardiogram-synchronized flow-sensitized 4-dimensional MR imaging at 3T in combination with advanced 3D visualization strategies to ascertain its feasibility for the assessment of local intracranial blood-flow patterns in vivo. In large arteries of healthy volunteers, the temporal and spatial evolution of blood flow was successfully visualized and revealed—for example, a helical flow pattern in the carotid siphon. In a patient with steno-occlusive neurovascular disease, stagnant and retrograde flow patterns were readily visible.