Artigo Acesso aberto Revisado por pares

Polymorphisms of NRF2 and NRF2 target genes in urinary bladder cancer patients

2014; Springer Science+Business Media; Volume: 140; Issue: 10 Linguagem: Inglês

10.1007/s00432-014-1733-0

ISSN

1432-1335

Autores

Edyta Reszka, Zbigniew Jabłonowski, Edyta Wieczorek, Ewa Jabłońska, Magdalena Beata Król, Jolanta Gromadzińska, Adam Grzegorczyk, Marek Sosnowski, Wojciech Wąsowicz,

Tópico(s)

Bladder and Urothelial Cancer Treatments

Resumo

NRF2 transcription factor is involved in modulation of various antioxidant and metabolic genes and, therefore, may modulate anti-carcinogenic potential. Association between polymorphisms of NRF2 and five NRF2-regulated genes and urinary bladder cancer (BC) risk was analyzed.

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