Carta Acesso aberto Revisado por pares

Xanthine oxidase inhibition for chronic heart failure: is allopurinol the next therapeutic advance in heart failure?

2005; BMJ; Volume: 91; Issue: 6 Linguagem: Inglês

10.1136/hrt.2004.057190

ISSN

1468-201X

Autores

Wolfram Doehner,

Tópico(s)

Inflammasome and immune disorders

Resumo

Abstract A substantial body of evidence has accumulated to suggest a role for the xanthine oxidase metabolic pathway in the pathophysiology of chronic heart failure and other cardiovascular diseases BNP, brain natriuretic peptideCHF, chronic heart failureNO, nitric oxideXO, xanthine oxidaseallopurinolheart failurexanthine oxidoreductase

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