Induction of HIV-1–Specific Mucosal Immune Responses Following Intramuscular Recombinant Adenovirus Serotype 26 HIV-1 Vaccination of Humans
2014; Oxford University Press; Volume: 211; Issue: 4 Linguagem: Inglês
10.1093/infdis/jiu485
ISSN1537-6613
AutoresLindsey R. Baden, Jinyan Liu, Hualin Li, Jennifer Johnson, Stephen R. Walsh, Jane A. Kleinjan, Brian A. Engelson, Lauren Peter, Peter Abbink, Danny A. Milner, Kevin Golden, Kyle L. Viani, Matthew D. Stachler, Benjamin J. Chen, Maria Grazia Pau, Mo Weijtens, Brittany R. Carey, Caroline A. Miller, Edith Swann, Mark Wolff, Hayley Loblein, Michael S. Seaman, Raphael Dolin, Dan H. Barouch,
Tópico(s)Herpesvirus Infections and Treatments
ResumoBackgroundDefining mucosal immune responses and inflammation to candidate human immunodeficiency virus type 1 (HIV-1) vaccines represents a current research priority for the HIV-1 vaccine field. In particular, it is unclear whether intramuscular immunization can elicit immune responses at mucosal surfaces in humans.
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