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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Contribution of Candida albicans ALS1 to the Pathogenesis of Experimental Oropharyngeal Candidiasis

2002; American Society for Microbiology; Volume: 70; Issue: 9 Linguagem: Inglês

10.1128/iai.70.9.5256-5258.2002

ISSN

1098-5522

Autores

Yasuki Kamai, Mikie Kubota, Yoko Kamai, Tsunemichi Hosokawa, Takashi Fukuoka, Scott G. Filler,

Tópico(s)

Infections and bacterial resistance

Resumo

ABSTRACT We investigated the contribution of Candida albicans ALS1 , which encodes a candidal adhesin, to the pathogenesis of experimental murine oropharyngeal candidiasis. Our results indicate that the ALS1 gene product is important for the adherence of the organism to the oral mucosa during the early stage of the infection.

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