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The Saccharomyces cerevisiae MADS-Box Transcription Factor Rlm1 Is a Target for the Mpk1 Mitogen-Activated Protein Kinase Pathway

1997; Taylor & Francis; Volume: 17; Issue: 4 Linguagem: Inglês

10.1128/mcb.17.4.1848

ISSN

1098-5549

Autores

Evdokia Dodou, Richard Treisman,

Tópico(s)

Plant Gene Expression Analysis

Resumo

Mutation ofSaccharomyces cerevisiae RLM1, which encodes a MADS-box transcription factor, confers resistance to the toxic effects of constitutive activity of the Mpk1 mitogen-activated kinase (MAPK) pathway.The Rlm1 DNA-binding domain, which is similar to that of the metazoan MEF2 transcription factors, is also closely related to that of a second S. cerevisiae protein, Smp1 (second MEF2-like protein), encoded by the YBR182C open reading frame (N.Demolis et al., Yeast 10:

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