Treatment targets in renal fibrosis
2007; Oxford University Press; Volume: 22; Issue: 12 Linguagem: Inglês
10.1093/ndt/gfm393
ISSN1460-2385
AutoresPeter Boor, Katarı́na Šebeková, Tammo Ostendorf, Jürgen Floege,
Tópico(s)Muscle and Compartmental Disorders
ResumoRenin-angiotensin-aldosterone (RAAS) and kallikrein-kinin systemAngiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor type 1 blockers (ARB) are undisputedly the first line drugs in combating renal fibrosis.These drugs, however, are not able to halt the progression completely and in some conditions, like aristocholic acid-induced renal fibrosis in rats, they are
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