Revisão Acesso aberto Revisado por pares

Treatment targets in renal fibrosis

2007; Oxford University Press; Volume: 22; Issue: 12 Linguagem: Inglês

10.1093/ndt/gfm393

ISSN

1460-2385

Autores

Peter Boor, Katarı́na Šebeková, Tammo Ostendorf, Jürgen Floege,

Tópico(s)

Muscle and Compartmental Disorders

Resumo

Renin-angiotensin-aldosterone (RAAS) and kallikrein-kinin systemAngiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor type 1 blockers (ARB) are undisputedly the first line drugs in combating renal fibrosis.These drugs, however, are not able to halt the progression completely and in some conditions, like aristocholic acid-induced renal fibrosis in rats, they are

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