Rapid Microtiter Method for Cytotoxicity Screening
1972; Elsevier BV; Volume: 61; Issue: 12 Linguagem: Inglês
10.1002/jps.2600611215
ISSN1520-6017
AutoresEng‐Shang Huang, Kuo‐Hsiung Lee, Claude A. Piantadosi, T. A. Geissman, Joseph S. Pagano,
Tópico(s)Polyomavirus and related diseases
ResumoAbstract A simple, rapid, and inexpensive microplate tissue culture method suitable for large-scale cytotoxicity screening is described. The test involves the use of several cell lines, normal human fibroblasts, laryngeal carcinoma, and virus-transformed human cells for the evaluation of the potency of cytotoxicity as well as the selectivity for cancerous tissue of a variety of sesquiterpene lactones, plant products, and synthetic compounds.
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