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Uterine rupture associated with misoprostol labor induction in women with previous cesarean delivery

2003; Elsevier BV; Volume: 113; Issue: 1 Linguagem: Inglês

10.1016/s0301-2115(03)00363-4

1872-7654

Halıl Aslan, Emine Unlu, Mehmet Ağar, Yavuz Ceylan,

Maternal and fetal healthcare

To review our experience with uterine rupture in patients undergoing a trial of labor with a history of previous cesarean delivery in which labor was induced with misoprostol.A retrospective chart review was used to select patients who underwent induction of labor with misoprostol during the period from February 1999 to June 2002. Women with a history of cesarean delivery were retrospectively compared with those without uterine scarring.Uterine rupture occurred in 4 of 41 patients with previous cesarean delivery who had labor induced with misoprostol. The rate of uterine rupture (9.7%) was significantly higher in patients with a previous cesarean delivery (P<0.001). No uterine rupture occurred in 50 patients without uterine scarring. Women with a history of cesarean delivery were more likely to have oxytocin augmentation than those without uterine scarring (41% versus 20%; P=0.037).Misoprostol induction of labor increases the risk of uterine rupture in women with a history of cesarean delivery.