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Insulin secretion and pancreatic exocrine function in patients with chronic pancreatitis

1979; Springer Science+Business Media; Volume: 16; Issue: 6 Linguagem: Inglês

10.1007/bf01223154

1432-0428

W. J. Kalk, A Vinik, W. P. U. Jackson, S Bank,

Pancreatitis Pathology and Treatment

The relationship between insulin responses to oral glucose and pancreatic exocrine function were examined in 15 patients with chronic pancreatitis. Good correlations were found between the insulin responses and exocrine pancreatic function measured as the concentrations of pancreatic enzymes in duodenal juice after intravenous cholecystokinin-pancreazymin (CCK-PZ). There appears to be a roughly parallel loss of endocrine and exocrine function in the course of chronic pancreatitis.