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Genetic analysis of actidione-resistant mutants in the Myxomycete Physarum polycephalum , Schw.

1966; Cambridge University Press; Volume: 8; Issue: 1 Linguagem: Inglês

10.1017/s0016672300009940

1469-5073

Jennifer Dee,

Chemical synthesis and alkaloids

1. Improved methods for the culture and preservation of Physarum polycephalum amoebae have been developed. 2. Strains of amoebae have been isolated which are stably resistant to 4, 8 or 16 μg./ml. actidione. 3. Sensitivity vs. resistance to 4 μg./ml. actidione is probably controlled by a single pair of alleles at a locus unlinked to the mating-type locus. 4. Plasmodia homozygous or heterozygous for the allele determining resistance at this locus are no more resistant to actidione than plasmodia homozygous for the allele determining sensitivity.