Cell quality in the ASTAMI study
2007; Oxford University Press; Volume: 28; Issue: 17 Linguagem: Inglês
10.1093/eurheartj/ehm125
ISSN1522-9645
Autores Tópico(s)Cardiac Fibrosis and Remodeling
ResumoSchachinger et al. 1 recently reported clinical improvement after treatment of acute myocardial infarction with intracoronary injection of autologous bone-marrow-derived mononuclear cells (MNCs) (the REPAIR-AMI Trial). Here, the authors discuss whether lack of improvement in global left ventricular function in our study, the ASTAMI study,2 could be related to impaired cell quality or insufficient cell numbers. We believe this is unlikely for the following reasons: 1. Comparable density gradient centrifugation techniques …
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