Editorial Revisado por pares

‘Close-to-ideal’ tumor boron targeting for boron neutron capture therapy is possible with ‘less-than-ideal’ boron carriers approved for use in humans

2015; Future Science Ltd; Volume: 6; Issue: 3 Linguagem: Inglês

10.4155/tde.14.108

ISSN

2041-6008

Autores

Amanda E. Schwint, Verónica A. Trivillin,

Tópico(s)

Medical Imaging Techniques and Applications

Resumo

Therapeutic DeliveryVol. 6, No. 3 Editorial'Close-to-ideal' tumor boron targeting for boron neutron capture therapy is possible with 'less-than-ideal' boron carriers approved for use in humansAmanda E Schwint & Verónica A TrivillinAmanda E SchwintAuthor for correspondence: E-mail Address: schwint@cnea.gov.arRadiation Pathology Division, Department of Radiobiology, National Atomic Energy Commission, Avenida General Paz 1499, B1650KNA San Martin, Provincia Buenos Aires, Argentina & Verónica A TrivillinRadiation Pathology Division, Department of Radiobiology, National Atomic Energy Commission, Avenida General Paz 1499, B1650KNA San Martin, Provincia Buenos Aires, ArgentinaPublished Online:8 Apr 2015https://doi.org/10.4155/tde.14.108AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: boron compounds approved for use in humansboron neutron capture therapy (BNCT)BPAGB-10optimization of boron tumor targetingReferences1 Hopewell JW, Morris GM, Schwint AE, Coderre JA. 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Boron neutron capture therapy for oral pre-cancer: proof of principle in an experimental animal model. Oral Dis. 19(8), 789–795 (2013).Crossref, Medline, CAS, Google Scholar18 Yamatomo N, Iwagami T, Kato I et al. Sonoporation as an enhancing method for boron neutron capture therapy for squamous cell carcinomas. Radiat. Oncol. 8, 280 (2013).Crossref, Medline, Google Scholar19 Capuani S, Gili T, Bozzali M et al. L-DOPA preloading increases the uptake of borophenylalanine in C6 glioma rat model: a new strategy to improve BNCT efficacy. Int. J. Radiat. Oncol. Biol. Phys. 72(2), 562–567 (2008).Crossref, Medline, CAS, Google Scholar20 Masunaga SI, Sakurai Y, Tano K et al. Effect of bevacizumab combined with boron neutron capture therapy on local tumor response and lung metastasis. Exper. Ther. Med. 8(1), 291–301 (2014).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByIn vivo polymerization of the dopamine-borate melanin precursor: A proof-of-concept regarding boron neutron-capture therapy for melanomaBIOCELL, Vol. 47, No. 4Using 157Gd doped carbon and 157GdF4 nanoparticles in proton-targeted therapy for effectiveness enhancement and thermal neutron reduction: a simulation study18 October 2022 | Scientific Reports, Vol. 12, No. 1Animal Tumor Models for Boron Neutron Capture Therapy Studies (Excluding Central Nervous System Solid Tumors)21 September 2022 | Cancer Biotherapy and Radiopharmaceuticals, Vol. 61Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-Functionalized Closo-Dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and In Vivo BNCT in the Hamster Cheek Pouch Oral Cancer Model20 July 2022 | Life, Vol. 12, No. 7Importance of radiobiological studies for the advancement of boron neutron capture therapy (BNCT)31 March 2022 | Expert Reviews in Molecular Medicine, Vol. 24Evaluation of local, regional and abscopal effects of Boron Neutron Capture Therapy (BNCT) combined with immunotherapy in an ectopic colon cancer modelThe British Journal of Radiology, Vol. 94, No. 1128Clinical Veterinary Boron Neutron Capture Therapy (BNCT) Studies in Dogs with Head and Neck Cancer: Bridging the Gap between Translational and Clinical Studies7 October 2020 | Biology, Vol. 9, No. 10Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model23 May 2019 | Radiation and Environmental Biophysics, Vol. 58, No. 3Different oral cancer scenarios to personalize targeted therapy: Boron Neutron Capture Therapy translational studiesAndrea Monti Hughes, Jessica A Goldfinger, Iara S Santa Cruz, Emiliano CC Pozzi, Silvia Thorp, Paula Curotto, Marcela A Garabalino, María E Itoiz, Mónica A Palmieri, Paula Ramos, Elisa M Heber, Romina F Aromando, David W Nigg, Hanna Koivunoro, Verónica A Trivillin & Amanda E Schwint11 June 2019 | Therapeutic Delivery, Vol. 10, No. 6Translational boron neutron capture therapy (BNCT) studies for the treatment of tumors in lung22 February 2019 | International Journal of Radiation Biology, Vol. 95, No. 5First experimental proof of Proton Boron Capture Therapy (PBCT) to enhance protontherapy effectiveness18 January 2018 | Scientific Reports, Vol. 8, No. 1Optimizing the Therapeutic Efficacy of Boron Neutron Capture Therapy (BNCT) for Different Pathologies12 July 2018Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer8 August 2017 | Radiation and Environmental Biophysics, Vol. 56, No. 4Boron neutron capture synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: radiobiological studies at RA-1 Nuclear Reactor in a model of antigen-induced arthritis in rabbits27 August 2016 | Radiation and Environmental Biophysics, Vol. 55, No. 4Current data regarding the structure-toxicity relationship of boron-containing compoundsToxicology Letters, Vol. 258 Vol. 6, No. 3 Follow us on social media for the latest updates Metrics Downloaded 45 times History Published online 8 April 2015 Published in print April 2015 Information© Future Science LtdKeywordsboron compounds approved for use in humansboron neutron capture therapy (BNCT)BPAGB-10optimization of boron tumor targetingFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in this manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download

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