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Reactions of Cobinamide with Glucose and Fructose

2012; Volume: 5; Issue: 3 Linguagem: Inglês

10.6060/mhc2012.120884m

1998-9539

Ilia А. Dereven’kov, Denis S. Salnikov, Nikita I. Shpagilev, Sergei V. Makarov, Ekaterina N. Tarakanova,

Methemoglobinemia and Tumor Lysis Syndrome

Kinetics of cobinamide (Cbi) reduction by glucose and fructose was studied at alkaline solutions.It was shown that the reaction of cobinamide with monosaccharides leads to the formation of Co(I) complex in contrast to the reduction of aquacobalamin (H 2 OCbl) resulting in the formation of Cbl(II).