Portal de Periódicos da CAPES

The role of methylmethacrylate monomer in the formation and haemodynamic outcome of pulmonary fat emboli

1998; British Editorial Society of Bone & Joint Surgery; Volume: 80; Issue: 1 Linguagem: Inglês

10.1302/0301-620x.80b1.7774

2044-5377

Amr Elmaraghy, B. Humeniuk, GI Anderson, E. Schemitsch, R R Richards,

Hip disorders and treatments

The Journal of Bone and Joint Surgery. British volumeVol. 80-B, No. 1 ResearchFree AccessThe role of methylmethacrylate monomer in the formation and haemodynamic outcome of pulmonary fat emboliA. W. ElMaraghy, B. Humeniuk, G. I. Anderson, E. H. Schemitsch, R. R. RichardsA. W. ElMaraghyResearch FellowSt. Michael's Hospital, Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, 55 Queen Street East, Suite 800, Toronto, Ontario, Canada M5CIR6., B. HumeniukResearch FellowSt. Michael's Hospital, Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, 55 Queen Street East, Suite 800, Toronto, Ontario, Canada M5CIR6., G. I. AndersonDiplomate ACVSDepartment of Surgery, Dalhousie University, 5981 University Avenue, Halifax, Nova Scotia, Canada B3H 3S5., E. H. SchemitschAssistant ProfessorSt. Michael's Hospital, Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, 55 Queen Street East, Suite 800, Toronto, Ontario, Canada M5CIR6., R. R. RichardsAssociate ProfessorSt. Michael's Hospital, Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, 55 Queen Street East, Suite 800, Toronto, Ontario, Canada M5CIR6.Published Online:1 Jan 1998https://doi.org/10.1302/0301-620X.80B1.0800156AboutSectionsPDF/EPUB ToolsAdd to FavouritesDownload CitationsTrack CitationsPermissions ShareShare onFacebookTwitterLinked InRedditEmail AbstractWe examined the roles of methylmethacrylate (MMA) monomer and cementing technique in the formation, and haemodynamic outcome, of pulmonary fat emboli. The preparation of the femoral canal and the cementing technique were studied in four groups of adult dogs as follows: control (no preparation); lavage; cement pressurisation; and cement pressurisation after lavage. We measured the intramedullary pressure, pulmonary artery pressure (PAP), pulmonary capillary wedge pressure and bilateral femoral vein levels of triglyceride, cholesterol and MMA monomer at rest and after reaming, lavage, and cementing.Femoral vein triglyceride and cholesterol levels did not vary significantly from resting levels despite significant elevations in intramedullary pressure with reaming, lavage and cementing (p = 0.001). PAP was seen to rise significantly with reaming (p = 0.0038), lavage (p = 0.0031), cementing (p = 0.0024) and cementing after lavage (p = 0.0028) while the pulmonary capillary wedge pressure remained unchanged.MMA monomer was detected in femoral vein samples when cement pressurisation was used. Intramedullary lavage before cementing had no significant effect on the MMA level. Haemodynamic evidence of pulmonary embolism was noted with reaming and intramedullary canal preparation, irrespective of the presence of MMA monomer. We found no relationship between MMA monomer level and intramedullary pressure, PAP or pulmonary capillary wedge pressure.Our findings suggest that the presence of MMA monomer in femoral venous blood has no effect on the formation of fat emboli or their pulmonary haemodynamic outcome during cemented hip arthroplasty.FiguresReferencesRelatedDetailsCited byArteriovenograma de cemento óseo en artroplastia de caderaRevista Española de Cirugía Ortopédica y Traumatología, Vol. 64, No. 6Cement arteriovenogram after hip arthroplastyRevista Española de Cirugía Ortopédica y Traumatología (English Edition), Vol. 64, No. 6On-Table and Short-Term Mortality: A Single-Institution Experience With Cementing All Hip Arthroplasties for Neck of Femur FracturesThe Journal of Arthroplasty, Vol. 35, No. 4Bone cement (PMMA) arterio-venogram following total hip arthroplasty – Case seriesJournal of Clinical Orthopaedics and Trauma, Vol. 9Animal models to assess the local and systemic effects of nailingJournal of Trauma and Acute Care Surgery, Vol. 76, No. 6The early response to major trauma and intramedullary nailingT. O. White, R. E. Clutton, D. Salter, D. Swann, J. Christie, C. M. Robinson1 June 2006 | The Journal of Bone and Joint Surgery. British volume, Vol. 88-B, No. 6 Vol. 80-B, No. 1 Metrics History Published online 1 January 1998 Published in print 1 January 1998 InformationCopyright © 1998, The British Editorial Society of Bone and Joint Surgery: All rights reservedPDF download