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Artigo Revisado por pares
BIBTEX RIS

Light-cleavable rapamycin dimer as an optical trigger for protein dimerization

2015; Royal Society of Chemistry; Volume: 51; Issue: 26 Linguagem: Inglês

10.1039/c4cc09442e

ISSN

1364-548X

Autores

Kalyn A. Brown, Yan Zou, David Shirvanyants, Jie Zhang, Subhas Samanta, Pavan K. Mantravadi, Nikolay V. Dokholyan, Alexander Deiters,

Tópico(s)

Click Chemistry and Applications

Resumo

Protein heterodimerization of FKBP12 and FRB can be optically controlled with a photocleavable rapamycin dimer.

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