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Bipolar disorder and multiple sclerosis

2007; Thieme Medical Publishers (Germany); Volume: 65; Issue: 4b Linguagem: Inglês

10.1590/s0004-282x2007000700016

1678-4227

Mariana Inés Ybarra, Marcos Aurélio Moreira, Carolina Reis Araújo, Marco Aurélio Lana–Peixoto, Antônio Lúcio Teixeira,

Bipolar Disorder and Treatment

Bipolar disorder may be overrepresented in multiple sclerosis (MS) patients. Although research in this area is limited, studies assessing the nature of this association have focused on genetic aspects, adverse reaction to drugs and brain demyelinating lesions. Herein we report three patients with MS that also presented bipolar disorder. The coexistence of neurological and psychiatric symptoms in most MS relapses highlights the relevance of biological factors in the emergence of mood disorders in these patients.