The Immunoglobulin Class, the Subclass and the Ratio of k:λ Light Chain of Autoantibodies to human Insulin in Insulin Autoimmune Syndrome
1989; Informa; Volume: 3; Issue: 4 Linguagem: Inglês
10.3109/08916938908997099
ISSN1607-842X
AutoresYasuko Uchigata, Yoko Eguchi, Sumiko Takayama-Hasumi, Yikimasa Hirata,
Tópico(s)Pancreatic function and diabetes
ResumoThe immunoglobulin class, subclass and the k: λ light chain ratio of insulin autoantibodies were determined in the sera of twenty-four patients with insulin autoimmune syndrome. All sera proved to be of the IgG immunoglobulin class but exhibited various IgG1:IgG2:IgG3:IgG4 ratios. The ratio of k:λ light chain ranged from 1:0.13 to 1:0.75 with the exceptions of two sera that were characterized as IgG1(k) and IgG1,(λ).
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