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Treatment and long-term follow-up of cats with suspected primary epilepsy

2012; SAGE Publishing; Volume: 15; Issue: 4 Linguagem: Inglês

10.1177/1098612x12464627

1532-2750

Ákos Pákozdy, Ali Asghar Sarchahi, Michael Leschnik, Alexander Tichy, Péter Halász, Johann G. Thalhammer,

Pharmacological Effects and Toxicity Studies

We report an evaluation of the treatment and outcome of cats with suspected primary epilepsy. Phenobarbital therapy was used alone or in combination with other anti-epileptic drugs. Outcome after treatment was evaluated mainly on the basis of number of seizures per year and categorised into four groups: seizure-free, good control (1-5 seizures per year), moderate control (6-10 seizures per year) and poor control (more than 10 seizures per year). About 40-50% of cases became seizure-free, 20-30% were considered good-to-moderately controlled and about 30% were poorly controlled depending on the year of treatment considered. The duration of seizure events after treatment decreased in 26/36 cats and was unchanged in eight cats. The subjective severity of seizure also decreased in 25 cats and was unchanged in nine cats. Twenty-six cats had a good quality of life, nine cats an impaired quality of life and one cat a bad quality of life. Despite being free of seizures for years, cessation of treatment may lead to recurrence of seizures in most cats.