Portal de Periódicos da CAPES

Catalytic Enantioselective Synthesis of Vicinal Dialkyl Arrays

2008; American Chemical Society; Volume: 73; Issue: 18 Linguagem: Inglês

10.1021/jo8010649

1520-6904

Anthoni W. van Zijl, Wiktor Szymański, Fernando López, Adriaan J. Minnaard, Ben L. Feringa,

Marine Sponges and Natural Products

With a consecutive "asymmetric allylic alkylation (AAA)/cross-metathesis (CM)/conjugate addition (CA)" protocol it is possible to synthesize either stereoisomer of compounds containing a vicinal dialkyl array with excellent stereoselectivity. The versatility of this protocol in natural product synthesis is demonstrated in the preparation of the ant pheromones faranal and lasiol.