Circulating MicroRNAs in gynecological malignancies: from detection to prediction
2014; BioMed Central; Volume: 3; Issue: 1 Linguagem: Inglês
10.1186/2162-3619-3-14
ISSN2162-3619
AutoresYa-Nan Zhao, Guan-Sheng Chen, Shun-Jia Hong,
Tópico(s)Cancer-related molecular mechanisms research
ResumoMicroRNAs (miRNAs) have been demonstrated to play critical roles in many physiological and pathophysiological processes. The presence of altered miRNA profiles in human body fluids has been reported for a number of diseases including gynecological malignancies. In this review, we summarized the current progresses of circulating miRNAs associated with malignancies in gynecology, with an emphasizing on the circulating miRNAs as diagnostic and prognostic biomarkers in ovarian cancer, endometrial carcinoma and cervical cancer.
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