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Tracking down the sources of experimental contamination in microbiome studies

2014; BioMed Central; Volume: 15; Issue: 12 Linguagem: Inglês

10.1186/s13059-014-0564-2

1474-760X

Sophie Weiss, Amnon Amir, Embriette R. Hyde, Jessica L. Metcalf, Se Jin Song, Rob Knight,

Microbial Community Ecology and Physiology

A recent report warns that DNA extraction kits and other laboratory reagents are considerable sources of contamination in microbiome experiments. The issue of contamination is particularly problematic for samples of low biomass.