Portal de Periódicos da CAPES

SQUINT: a multiple alignment program and editor

2007; Oxford University Press; Volume: 23; Issue: 12 Linguagem: Inglês

10.1093/bioinformatics/btm128

1367-4811

Matthew Goode, Allen G. Rodrigo,

RNA and protein synthesis mechanisms

Abstract Summary: SQUINT is a sequence alignment tool, and combines both automated progressive sequence alignment with facilities for manual editing. The program imports nucleotide or amino acid sequence multiple alignment files in standard formats, and permits users to view two translations of the same multiple alignment simultaneously. Edits in one view are instantaneously reflected in the other, and the scoring cost of the changes are shown in real-time. Progressive multiple alignments, using a variety of alignment parameters, can be performed on any block of sequences, including blocks embedded in the existing alignment. Availability: The software is freely available for download at http://www.cebl.auckland.ac.nz Contact: a.rodrigo@auckland.ac.nz