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Double-Blind Controlled Study of L-Dopa Therapy in Schizophrenia

1975; Wiley; Volume: 29; Issue: 2 Linguagem: Inglês

10.1111/j.1440-1819.1975.tb02330.x

1440-1819

Kazutoyo Inanaga, Yoichi Nakazawa, Katsumi Inoue, Hisayuki Tachibana, Masachika Oshima, Tatayu Kotorii, Masatoshi Tanaka, Nobuya Ogawa,

Neurotransmitter Receptor Influence on Behavior

Psychiatry and Clinical NeurosciencesVolume 29, Issue 2 p. 123-143 Double-Blind Controlled Study of L-Dopa Therapy in Schizophrenia Kazutoyo Inanaga M.D., Kazutoyo Inanaga M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorYoichi Nakazawa M.D., Yoichi Nakazawa M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorKatsumi Inoue M.D., Katsumi Inoue M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorHisayuki Tachibana M.D., Hisayuki Tachibana M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorMasachika Oshima M.D., Masachika Oshima M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorTatayu Kotorii M.D., Tatayu Kotorii M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorMasatoshi Tanaka M.D., Masatoshi Tanaka M.D. Institute of Brain Diseases, Kurume University School of Medicine, KurumeSearch for more papers by this authorNobuya Ogawa M.D., Nobuya Ogawa M.D. Department of Pharmacology, Kyushu University Faculty of Pharmaceutical Sciences, FukuokaSearch for more papers by this author Kazutoyo Inanaga M.D., Kazutoyo Inanaga M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorYoichi Nakazawa M.D., Yoichi Nakazawa M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorKatsumi Inoue M.D., Katsumi Inoue M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorHisayuki Tachibana M.D., Hisayuki Tachibana M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorMasachika Oshima M.D., Masachika Oshima M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorTatayu Kotorii M.D., Tatayu Kotorii M.D. Department of Neuropsychiatry, Kurume University School of Medicine, KurumeSearch for more papers by this authorMasatoshi Tanaka M.D., Masatoshi Tanaka M.D. Institute of Brain Diseases, Kurume University School of Medicine, KurumeSearch for more papers by this authorNobuya Ogawa M.D., Nobuya Ogawa M.D. Department of Pharmacology, Kyushu University Faculty of Pharmaceutical Sciences, FukuokaSearch for more papers by this author First published: June 1975 https://doi.org/10.1111/j.1440-1819.1975.tb02330.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Andén, N. E., Engel, J. and Rubenson, A.: Mode of action of L-Dopa on central noradrenaline mechanisms, Naunyn-Schmiedeberg's Arch Pharmacol, 273: 1–10, 1972. 2 Angrist, B., Sathananthan, G. and Gershon, S.: Behavioral effects of L-Dopa in schizophrenic patients, Psychopharmacologia (Berl.), 31: 1–12, 1973. 3 Asano, T., Noma, T., Matsuda, K., Ikeda, H. and Otsuki, S.: Effects of L-Dopa on the hypochondriac complaints of the chronic psychotics, Clin Psychiat, 15: 745–751, 1973 (in Japanese). 4 Barbeau, A.: L-Dopa therapy in Parkinson's disease'A critical review of nine years' experience, Canad Med Ass J, 101: 791–800, 1969. 5 Goodwin, F. K.: Behavioral effects of L-Dopa in man, In: Psychiatric complications of medical drugs. 149–174, 1972, R. I. Shader, Raven Press, New York . 6 Inanaga, K., Oshima, M., Tachibana, H., Nakamura, K. and Koketsu, K.: Three cases of schizophrenia treated with L-Dopa, Kurume Med J, 18: 161–168, 1971. 7 Inanaga, K., Inoue, K., Tachibana, H., Oshima, M. and Kotorii, T.: Effect of L-Dopa in schizophrenia, Folia Psychiat Neurol Jap, 26: 145–157, 1972. 8 Inanaga, K. and Tanaka, M.: Effects of L-Dopa on schizophrenia, In: Psychopharmacology, Sexual Disorders and Drug Abuse, T. A. Ban et al. (ed.), 229–233, 1973, North-Holland Publishing Co., Amsterdam . 9 Kawamura, T., Asada, N., Kimura, N. and Tsukue, I.: Psychiatric clinical findings of L-Dopa effect, Especially for psychic symptom and drug-induced parkinsonian symptom in schizophrenia. Shinryo, 23: 826–851, 1971 (in Japanese). 10 Nishikawa, K., Higasayama, I. and Kasahara, T.: L-Dopa therapy of chronic schizophrenia (with the main symptoms, lack of spontaneity and emotional blunting), Shinryo and Shinyaku, 9: 1439–1450, 1972 (in Japanese). 11 Ogura, C., Nakao, T., Kishimoto, A., Okuma, T., Inagaki, T. and Motoike, M.: Effects of biogenic amine precursor (L-Dopa) on schizophrenia, Jap J Clin Psychiat, 3: 1115–1124, 1974 (in Japanese). 12 Otsuka, T., Kumashiro, E., Mizushima, S., Maruko, K., Koizumi, S. and Unno, Y.: The effect of L-Dopa on schizophrenia, Jap J Clin Psychiat, 3: 629–637, 1974 (in Japanese). 13 Ritvo, E. R., Yuwiler, A., Geller, E., Kales, A., Rashkis, S., Schicor, A., Plotkin, S., Axelrod, R. and Howard, C.: Effects of L-Dopa in autism, J Autism and Child Schizophren, 1: 190–205, 1971. 14 Sarai, K., Kimura, N., Ishii, T., Iseki, K., Imada, H., Kawamura, T., Kino, M. and Echigo, T.: Possibility of amine precursor-therapy on schizophrenics by experimental study with L-Dopa, Clin Psychiat, 15: 189–196, 1973 (in Japanese). 15 Sathananthan, G., Angrist, B. M. and Gershon, S.: Response threshold to L-Dopa in psychiatric patients. Biol Psychiat, 7: 139–146, 1973. 16 Stein, L. and Wise, C. D.: Possible etiology of schizophrenia: progressive damage to the noradrenergic reward system by 6-hydroxydopamine. Science, 171: 1032–1036, 1971. 17 Wise, C. D. and Stein, L.: Dopamine-β-hydroxylase deficits in the brains of schizophrenic patients. Science, 181: 344–347, 1973. 18 Yamauchi, I.: The effect of L-Dopa on schizophrenia. Clin Psychiat, 14: 941–949, 1972 (in Japanese). 19 Yaryura-Tobias, J., Diamond, B. and Merlis, S.: The action of L-Dopa on schizophrenic patients (A preliminary report). Curr Ther Res, 12: 528–531, 1970. Citing Literature Volume29, Issue2June 1975Pages 123-143 ReferencesRelatedInformation