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Clinical review: The ABC of weaning failure - a structured approach

2010; BioMed Central; Volume: 14; Issue: 6 Linguagem: Inglês

10.1186/cc9296

1466-609X

Leo Heunks, Johannes G. van der Hoeven,

Cardiac Arrest and Resuscitation

About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing a treatment strategy require a dedicated clinician with in-depth knowledge of the pathophysiology of weaning failure. This review presents a structural framework ('ABCDE') for the assessment and treatment of difficult-to-wean patients. Earlier recognition of the underlying causes may expedite weaning from mechanical ventilation.