The Hoesch Test: Bedside Screening for Urinary Porphobilinogen in Patients with Suspected Porphyria
1974; American Association for Clinical Chemistry; Volume: 20; Issue: 11 Linguagem: Inglês
10.1093/clinchem/20.11.1438
ISSN1530-8561
AutoresJoel M. Lamon, Torben K. With, Allan G. Redeker,
Tópico(s)Heme Oxygenase-1 and Carbon Monoxide
ResumoAbstract A little-known procedure for porphobilinogen screening, the Hoesch test, was examined for sensitivity, specificity, and utility as compared to the Watson-Schwartz test. The data demonstrate that its sensitivity is similar to that of the Watson-Schwartz test. The Hoesch test, however, is without false-positive reactions secondary to urobilinogen, and its simplicity makes it easier to use and more easily interpretable. We conclude that the Hoesch test should replace the Watson-Schwartz test for urine porphobilinogen screening in suspected cases of acute intermittent and variegate porphyria.
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