Iridium‐Complex‐Functionalized Fe 3 O 4 /SiO 2 Core/Shell Nanoparticles: A Facile Three‐in‐One System in Magnetic Resonance Imaging, Luminescence Imaging, and Photodynamic Therapy
2008; Wiley; Volume: 4; Issue: 2 Linguagem: Inglês
10.1002/smll.200700283
ISSN1613-6829
AutoresChih‐Wei Lai, YH Wang, Cheng‐Hsuan Lai, Meng‐Ju Yang, Chun‐Yen Chen, Pi‐Tai Chou, Chi‐Shun Chan, Yün Chi, Yi‐Chun Chen, Jong‐Kai Hsiao,
Tópico(s)Molecular Sensors and Ion Detection
ResumoHighly uniform Fe3O4/SiO2 core/shell nanoparticles functionalized by phosphorescent iridium complexes (Ir) have been strategically designed and synthesized. The Fe3O4/SiO2(Ir) nanocomposite demonstrates its versatility in various applications: the magnetic core provides the capability for magnetic resonance imaging and the great enhancement of the spin-orbit coupling in the iridium complex makes it well suited for phosphorescent labeling and simultaneous singlet oxygen generation to induce apoptosis.
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