Virulence Of Entamoeba Histolytica : A Challenge For Human Health Research
2011; Future Medicine; Volume: 6; Issue: 3 Linguagem: Inglês
10.2217/fmb.11.2
ISSN1746-0921
AutoresFernando Anaya-Velázquez, Felipe Padilla‐Vaca,
Tópico(s)Parasitic Infections and Diagnostics
ResumoFuture MicrobiologyVol. 6, No. 3 EditorialVirulence of Entamoeba histolytica: a challenge for human health researchFernando Anaya-Velázquez & Felipe Padilla-VacaFernando Anaya-Velázquez† Author for correspondence & Felipe Padilla-VacaDepartamento de Biología, División de CNE, Universidad de Guanajuato, Noria Alta s/n, Guanajuato, Gto. 36050, MéxicoPublished Online:31 Mar 2011https://doi.org/10.2217/fmb.11.2AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: biological activitiesdeterminants of virulenceEntamoeba histolyticapathogenesisvirulence factorsBibliography1 Ali IK, Clark CG, Petri WA Jr: Molecular epidemiology of amebiasis. Infect. Genet. Evol.8,698–707 (2008).Crossref, Medline, CAS, Google Scholar2 Olivos-García A, Saavedra E, Ramos-Martínez E, Nequiz M, Pérez-Tamayo R: Molecular nature of virulence in Entamoeba histolytica. Infect. Genet. Evol.9,1033–1037 (2009).Crossref, Medline, CAS, Google Scholar3 Padilla-Vaca F, Anaya-Velázquez F: Insights into Entamoeba histolytica virulence modulation. Infect. Disord. Drug Targets10,242–250 (2010).Crossref, Medline, CAS, Google Scholar4 González A, Monterrubio D, Nequiz M et al.: Localization of Entamoeba histolytica amebopore in amebic liver abscesses in hamsters. Ann. NY Acad. Sci.1149,375–379 (2008).Crossref, Medline, CAS, Google Scholar5 Irmer H, Tillack M, Biller L et al.: Major cysteine peptidases of Entamoeba histolytica are required for aggregation and digestion of erythrocytes but are dispensable for phagocytosis and cytopathogenicity. Mol. Microbiol.72,658–667 (2009).Crossref, Medline, CAS, Google Scholar6 Sen A, Chatterjee NS, Akbar MA, Nandi N, Das P: The 29-kilodalton thiol-dependent peroxidase of Entamoeba histolytica is a factor involved in pathogenesis and survival of the parasite during oxidative stress. Eukaryot. Cell6,664–673 (2007).Crossref, Medline, CAS, Google Scholar7 Santi-Rocca J, Weber C, Guigon G, Sismeiro O, Coppée JY, Guillén N: The lysine- and glutamic acid-rich protein KERP1 plays a role in Entamoeba histolytica liver abscess pathogenesis. Cell Microbiol.10,202–217 (2008).Medline, CAS, Google Scholar8 Freitas MA, Fernandes HC, Calixto VC et al.: Entamoeba histolytica: cysteine proteinase activity and virulence. Focus on cysteine proteinase 5 expression levels. Exp. Parasitol.122,306–309 (2009).Crossref, Medline, CAS, Google Scholar9 Mendoza-Macías CL, Barrios-Ceballos MP, Anaya-Velázquez F, Nakada-Tsukui K, Nozaki T, Padilla-Vaca F: Entamoeba histolytica: molecular cloning and characterization of a novel neutral sphingomyelinase. Exp. Parasitol.125,279–285 (2010).Crossref, Medline, CAS, Google Scholar10 He C, Nora GP, Schneider EL et al.: A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target. J. Biol. Chem.285,18516–18527 (2010).Crossref, Medline, CAS, Google Scholar11 Ramos-Martínez E, Olivos-García A, Saavedra E et al.: Entamoeba histolytica: oxygen resistance and virulence. Int. J. Parasitol.39,693–702 (2009).Crossref, Medline, CAS, Google Scholar12 Davis PH, Zhang X, Guo J, Townsend RR, Stanley SL Jr: Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulence. Mol. Microbiol.61,1523–1532 (2006).Crossref, Medline, CAS, Google Scholar13 Biller L, Davis PH, Tillack M, Matthiesen J, Lotter H, Stanley SL Jr: Differences in the transcriptome signatures of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties. BMC Genomics11,63 (2010).Crossref, Medline, Google Scholar14 Ehrenkaufer GM, Singh U: Transcriptional regulatory networks in Entamoeba histolytica. Curr. Drug Targets9,931–937 (2008).Crossref, Medline, CAS, Google Scholar15 Gilchrist CA, Houpt E, Trapaidze N et al.: Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome. Mol. Biochem. Parasitol.147,163–176 (2006).Crossref, Medline, CAS, Google Scholar16 Vicente JB, Ehrenkaufer GM, Saraiva LM, Teixeira M, Singh U: Entamoeba histolytica modulates a complex repertoire of novel genes in response to oxidative and nitrosative stresses: implications for amebic pathogenesis. Cell Microbiol.11,51–69 (2009).Crossref, Medline, CAS, Google Scholar17 Baxt LA, Rastew E, Bracha R, Mirelman D, Singh U: Downregulation of an Entamoeba histolytica rhomboid protease reveals roles in regulating parasite adhesion and phagocytosis. Eukaryot. Cell9,1283–1293 (2010).Crossref, Medline, CAS, Google Scholar18 Biller L, Schmidt H, Krause E et al.: Comparison of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties. Proteomics9,4107–4120 (2009).Crossref, Medline, CAS, Google Scholar19 Mirelman D, Anbar M, Bracha R: Trophozoites of Entamoeba histolytica epigenetically silenced in several genes are virulence-attenuated. Parasite15,266–274 (2008).Crossref, Medline, CAS, Google Scholar20 Lejeune M, Rybicka JM, Chadee K: Recent discoveries in the pathogenesis and immune response toward Entamoeba histolytica. Future Microbiol.4,105–118 (2009).Link, CAS, Google Scholar21 Mendoza-Macías CL, Barrios-Ceballos MP, de la Peña LP et al.: Entamoeba histolytica: effect on virulence, growth and gene expression in response to monoxenic culture with Escherichia coli 055. Exp. Parasitol.121,167–174 (2009).Crossref, Medline, CAS, Google Scholar22 Lorenzi HA, Puiu D, Miller JR et al.: New assembly, reannotation and analysis of the Entamoeba histolytica genome reveal new genomic features and protein content information. PLoS Negl. Trop. Dis.4,E716 (2010).Crossref, Medline, Google Scholar23 Mirelman D, Ankri S, Katz U, Padilla-Vaca F, Bracha R: Pathogenesis of Entamoeba histolytica depends on the concerted action of numerous virulence factors. Arch. Med. Res.31(4 Suppl.),S214–S215 (2000).Crossref, Medline, CAS, Google Scholar24 Bansal D, Ave P, Kerneis S et al.: An ex-vivo human intestinal model to study Entamoeba histolytica pathogenesis. PLoS Negl. Trop. Dis.3,E551 (2009).Crossref, Medline, Google Scholar25 Solis CF, Santi-Rocca J, Perdomo D, Weber C, Guillén N: Use of bacterially expressed dsRNA to downregulate Entamoeba histolytica gene expression. PLoS ONE4,E8424 (2009).Crossref, Medline, Google ScholarFiguresReferencesRelatedDetailsCited ByAttenuation of In Vitro and In Vivo Virulence Is Associated with Repression of Gene Expression of AIG1 Gene in Entamoeba histolytica21 March 2023 | Pathogens, Vol. 12, No. 3Immune Dysfunction during Enteric Protozoal Infection: The Current Trends25 August 2021Relationships between food and diseases: What to know to ensure food safetyFood Research International, Vol. 137Epidemiological Prevalence of Entamoeba histolytica Infections Among the Patients Attending Nyanza District Hospital, Rwanda in 201825 December 2019 | International Journal of Epidemiologic Research, Vol. 6, No. 4Plasma membrane damage repair is mediated by an acid sphingomyelinase in Entamoeba histolytica28 August 2019 | PLOS Pathogens, Vol. 15, No. 8Contribution of neutral sphingomyelinases to in vitro virulence of Entamoeba histolyticaExperimental Parasitology, Vol. 194Iron-modulated virulence factors of Entamoeba histolyticaAurora Gastelum-Martínez, Claudia León-Sicairos, Laura Plata-Guzmán, Liliana Soto-Castro, Nidia León-Sicairos & Mireya de la Garza21 September 2018 | Future Microbiology, Vol. 13, No. 11Binding and Endocytosis of Bovine Hololactoferrin by the Parasite Entamoeba histolyticaBioMed Research International, Vol. 2015Entamoeba histolyticaEnteric Protozoa in the Developed World: a Public Health PerspectiveClinical Microbiology Reviews, Vol. 25, No. 3WITHDRAWN: Use of a recombinant Entamoeba histolytica cysteine proteinase antigen to evaluation of the efficacy of immune protective responses in miniature pigsExperimental ParasitologyIncreased serum nitric oxide and malondialdehyde levels in patients with acute intestinal amebiasisAsian Pacific Journal of Tropical Biomedicine, Vol. 1, No. 6 Vol. 6, No. 3 STAY CONNECTED Metrics Downloaded 667 times History Published online 31 March 2011 Published in print March 2011 Information© Future Medicine LtdKeywordsbiological activitiesdeterminants of virulenceEntamoeba histolyticapathogenesisvirulence factorsFinancial & competing interests disclosureThe authors would like to thank CONACYT, México and University of Guanajuato for their support for this work. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download
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